NCT03971981

Xylitol Chewing-gums: Concentration in Saliva and Antibacterial Effect

Xylitol Chewing-gums: Concentration in Saliva and Antibacterial Effect (In-vivo and In-vitro Study)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Università degli Studi di Sassari · Academic / Other
• Sex: All
• Age: 19 Years – 26 Years
• Healthy volunteers: Accepted

Summary

a double-blind cross-over in vivo study was performed to measure the salivary concentration of Xylitol released from the two chewing gums containing different amount of the polyol. The study had a cross-over design: the first half of the sample used the chewing-gum with Xylitol as the only sweeteners (64.5% of chewing-gum weight) and the other half use the chewing-gum with Xylitol among the sweeteners (22% of chewing-gum weight), after a 7-days wash-out period, the two sub-groups inverted the chewing gums. Subjects were instructed to consume the products as they normally would be consumed.

Detailed description

x

Conditions

• Dental Caries
• Periodontal Diseases

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	100% Xylitol Gum	Subjects were instructed to consume the gums as they normally would be consumed.
DIETARY_SUPPLEMENT	22% Xylitol Gum	Subjects were instructed to consume the gums as they normally would be consumed.

Timeline

• Start date: 2018-02-01
• Primary completion: 2018-05-31
• Completion: 2019-05-28
• First posted: 2019-06-03
• Last updated: 2019-06-03

Locations

1 site across 1 country: Italy