NCT03883022

Vancomycin Powder Combined With Autogenous Bone Graft as a Prevention for Post-operative Infection for Spine Surgery

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: Taipei Veterans General Hospital, Taiwan · Other Government
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Deep surgical site infection (DSSI) is one of the most challenging complications for spinal surgeons and can lead to a poor clinical outcome. This ambispective study was designed to examine the effect of vancomycin powder mixed with autogenous bone graft and bone substitute on preventing deep surgical site infection (DSSI) in degenerative lumbar fusion surgeries as well as any interference with bony fusion.

Conditions

• Spinal Fusion
• Spinal Stenosis
• Spondylolisthesis

Interventions

Type	Name	Description
DRUG	with U-VANCO (vancomycin hydrochloride)	1 gm or 2 gm mixed with autogenous cancellous bone graft
DRUG	without U-VANCO (vancomycin hydrochloride)	no vancomycin added

Timeline

• Start date: 2018-09-03
• Primary completion: 2027-09-12
• Completion: 2027-12-31
• First posted: 2019-03-20
• Last updated: 2019-03-20

Locations

1 site across 1 country: Taiwan