NCT03771014

A Feasibility Study of Early Mobilisation Programmes in Critical Care

EMPRESS: A Feasibility Study of Early Mobilisation Programmes in Critical Care

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: University Hospital Southampton NHS Foundation Trust · Academic / Other
• Sex: All
• Age: 42 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to determine the feasibility of delivering a very early mobility rehabilitation program in Intensive Care Units (ICU), within the context of a randomised controlled trial (RCT). This will inform the design of a future RCT investigating very early ICU rehabilitation in the UK National Health Service.

Detailed description

Early ICU-based physical rehabilitation may benefit patients with acute severe respiratory failure by attenuating the development of severe and persistent weakness and impaired physical function seen in these patients. Muscle wasting occurs early (within 12 hours) and progresses rapidly after ICU admission. Patients may suffer from consequent physical impairment for months or years following their discharge. ICU based rehabilitation has the potential to improve physical function outcomes, through mitigating muscle wasting. The investigators have successfully introduced a very early ICU mobility program in their institution, which results in increased ventilator free days and reduced length of ICU stay. The primary aim is to investigate whether this method will work in other ICUs. EMPRESS will test the feasibility of running this intervention as an RCT. The results and a concurrent process evaluation will inform the design of a future, multi-centre randomised controlled trial.

Conditions

• Critical Illness

Interventions

Type	Name	Description
OTHER	Early mobility	This progressive mobility pathway commenced with passive cycling within 48 hours of intubation and ventilation and progressing through assisted cycling, active cycling, bed exercises, sitting, mobilising out of bed to walking

Timeline

• Start date: 2019-05-28
• Primary completion: 2022-09-23
• Completion: 2022-09-23
• First posted: 2018-12-10
• Last updated: 2022-10-27

Locations

1 site across 1 country: United Kingdom