NCT03603236

Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease

Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease With Clinical Periodontal, Biochemical and Microbiological Data

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Recep Tayyip Erdogan University Training and Research Hospital · Academic / Other
• Sex: Female
• Age: 21 Years – 34 Years
• Healthy volunteers: Accepted

Summary

The primary objective of the study is to assess the incidence and severity of the periodontal infection of patients with preeclampsia. The secondary objective of the study is to analyze the relationship between preeclampsia and periodontal infection, using clinical, biochemical and microbiological methods.

Detailed description

Preeclampsia is identified as an important cause for mother and newborn mortality. Inspite of extensive research, the exact etiological relations have not been established. Periodontal disease is a subclinical and persistent infection source which induces the systemic inflammatory reactions and increases the risk of preeclampsia. It is believed that the results will set light to the etiology of preeclampsia and will help to develop strategies to prevent the disease.

Conditions

• Preeclampsia
• Periodontal Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	preeclampsia	liver function tests, kidney function tests and platelets measures the ratio of protein to creatinine
DIAGNOSTIC_TEST	control	liver function tests, kidney function tests and platelets measures the ratio of protein to creatinine

Timeline

• Start date: 2018-02-17
• Primary completion: 2018-09-17
• Completion: 2018-12-15
• First posted: 2018-07-27
• Last updated: 2018-07-27

Locations

5 sites across 2 countries: Turkey (Türkiye), United Kingdom