NCT03578796

Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Prospective Cohort Study

Cognitive Impairment in ALS: Screening Tools, Experiences and Prognosis

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 31 (actual)
• Sponsor: Haukeland University Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This study evaluate use of a translated Norwegian version of the Edinburgh cognitive and behavioral amyotrophic lateral sclerosis screen (ECAS-N) as an early predictor in car-driving, working and use of advanced life-prolonging therapy.

Detailed description

Cognitive impairment is present in about 30-50% of the patients with amyotrophic lateral sclerosis (ALS). Screening of cognitive and behavioral impairment is a distinct recommendation in ALS-specific health care. However, knowledge in how cognitive impairment shall influence health-care professionals' information given to patients and in decision making is lacking. One of the major challenges in ALS management is the decision-making on advanced therapy. There is a lack of knowledge in how cognitive impairment in ALS shall be interfere on complex medical treatment that will affect quality of life or life itself. This means significant implications not only to the ALS patient and the community, but also the family and especially the spouse. Thus, further investigation of the ECAS-N and its potential in clinical use is needed. The scale may contribute a more proactive treatment better tailored to individual needs. The objective is to evaluate if the ECAS-N can be applied as an early predictor in car-driving, working and use of advanced life-prolonging therapy

Conditions

• Amyotrophic Lateral Sclerosis
• Cognitive Impairment

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	ECAS-N	assessing ALS-specific cognitive impairment
DIAGNOSTIC_TEST	MoCA	assessing cognitive impairment
DIAGNOSTIC_TEST	CDR	assessing global cognitive impairment, as well as possible diagnosis- and Level of dementia
OTHER	Questionnaire	Questions related to work situation and car driving

Timeline

• Start date: 2017-05-01
• Primary completion: 2022-12-31
• Completion: 2026-12-31
• First posted: 2018-07-06
• Last updated: 2024-10-30

Locations

1 site across 1 country: Norway