NCT03368794

Naloxone to TReatment Entry in the Emergency Setting

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Anders C Håkansson · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study tests a structured referral process for opioid overdose survivors, from pre-hospital emergency care to long-term treatment of the individual's substance use-related disorder.

Detailed description

Randomized controlled trial. Subjects are included if they are being treated by an ambulance in the Malmö uptake are for an opioid overdose requiring naloxone antidote administration, and if they sign informed written consent to the study. Subjects are randomized by ambulance staff to either an active intervention, or a control condition: Intervention: A telephone alert signal is sent from ambulance staff after successful naloxone reversal of an opioid overdose, leading to an active outreach effort from the staff of the addiction research facility, where staff locate the individual and offer her/him formal inclusion in the study. Control: No telephone alert signal is sent, and the active outreach procedure is not carried out. Ambulance staff hand over written information to the individual about how she/he can apply actively for treatment. Primary outcome is entry into formal assessment and treatment of the substance use disorder.

Conditions

• Opioid Dependence
• Opioid Intoxication
• Substance Use Disorders

Interventions

Type	Name	Description
BEHAVIORAL	Active treatment referral of opioid overdose survivors to long-term treatment	Telephone alert and outreach for inclusion, assessment and intake into long-term evidence-based treatment of the substance use disorder.
BEHAVIORAL	Control	Written information from ambulance staff to the patient about how to seek treatment. Patient is able to contact the research treatment facility through a specific phone number, making it possible to study treatment entry in the information-only control condition.

Timeline

• Start date: 2017-09-15
• Primary completion: 2021-03-12
• Completion: 2021-03-12
• First posted: 2017-12-11
• Last updated: 2021-03-16

Locations

1 site across 1 country: Sweden