NCT03256539

Napping, Sleep, Cognitive Decline and Risk of Alzheimer's Disease

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to pilot test a non-pharmacological (behavioral) treatment program targeting improved cognition through improving 24-h sleep-wake cycle in people with mild cognitive impairment (MCI) or mild Alzheimer's disease. A treatment program incorporating bright light therapy and a modified cognitive behavioral therapy for insomnia will be developed to address 24-hour patterns of sleep. We will then pilot test its feasibility and explore its preliminary effects on improving sleep/napping and cognition in patients with MCI or mild Alzheimer's disease.

Conditions

• Sleep
• Alzheimer Disease
• Cognitive Impairment
• Aging
• CBT

Interventions

Type	Name	Description
BEHAVIORAL	Sleep intervention	Behavioral sleep intervention program
BEHAVIORAL	Placebo intervention	Quasi-desensitization intervention for insomnia (which does not include any of the active components of CBT-I but implemented in the same frequency and duration)

Timeline

• Start date: 2021-08-12
• Primary completion: 2024-01-31
• Completion: 2024-01-31
• First posted: 2017-08-22
• Last updated: 2025-11-14
• Results posted: 2025-11-14

Locations

1 site across 1 country: United States