NCT03252821

Effects of High-intensity Training Compared to Resistance Training in Cancer Patients Undergoing Radiotherapy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to assess the impact of a high-intensity aerobic training and resistance training on fatigue in prostate, head and neck and rectum cancer patients undergoing radiotherapy. A three-arm randomized controlled trial will be conducted. Patients will be randomised into either a high-intensity aerobic training group or a resistance training group or a control group. Participants in the training groups will exercised for five to eight weeks. Exercise sessions will be take place 3 days per week under the supervision of an experienced therapist. Subjects will be assessed at baseline and post-intervention. The primary outcome will be fatigue measured using the FACIT-fatigue questionnaire. The secondary outcomes will be: functional capacity, quality of life, executive functions, sleep disturbances, somnolence syndrome, insomnia, depression symptoms.

Conditions

• Prostate Cancer
• Head and Neck Cancer
• Rectum Cancer

Interventions

Type	Name	Description
BEHAVIORAL	High-intensity interval training	High-intensity interval training sessions will be conducted on cycle ergometers or treadmill with heart rate measured throughout each session.
BEHAVIORAL	Resistance training	Resistance exercise will be performed on eight exercises targeting major muscle groups at 60% to 85% of their estimated one-repetition maximum (1RM).

Timeline

• Start date: 2017-08-15
• Primary completion: 2019-09-01
• Completion: 2019-09-20
• First posted: 2017-08-17
• Last updated: 2020-03-17

Locations

1 site across 1 country: Belgium