NCT03246425

Influence of Mechanical Ventilation Mode on Arterial Pressure Variations- a Pilot Study

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: State University of New York - Upstate Medical University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Mechanical ventilation has been known to produce changes in the flow of blood through the major blood vessels in the body. These changes may go undetected, but with continuous arterial blood pressure measurements, changes in the arterial waveform can be visualized. Although we know that these arterial pressure variations occur during mechanical ventilation, little is known about the effects of various modes of mechanical ventilation on these changes. The most common modes of ventilation used in ICU are Volume control, Pressure control and Airway pressure release ventilation. Objective We have designed a prospective randomized pilot study to determine the effects of the commonly used ventilator modes on the arterial pressure.

Conditions

• Blood Pressure
• Critical Illness
• Hypovolemia

Interventions

Type	Name	Description
OTHER	Ventilator mode change	The enrolled subjects will be moved from the baseline mode to another mode of ventilation and the changes in the arterial pulse will be observed
DEVICE	Monitoring of blood pressure variation	The changes in the blood pressure will be measured in the form of Stroke Volume Variation using SVV using Vigileo (Edward Life sciences) monitor

Timeline

• Start date: 2016-09-12
• Primary completion: 2017-09-11
• Completion: 2017-09-11
• First posted: 2017-08-11
• Last updated: 2021-10-22

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study