NCT03207048

A Study of Repetitive Transcranial Magnetic Stimulation in Bipolar Patients

Repetitive Transcranial Magnetic Stimulation (rTMS) to Improve Cognitive Function and Prevent Relapses in Bipolar Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: Guangzhou Psychiatric Hospital · Other Government
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study will investigate the effect of Repetitive transcranial magnetic stimulation (rTMS) on cognition and long-term clinical outcomes of bipolar patients.

Detailed description

Cognitive deficits are core features of bipolar disorder. Preliminary evidence shows that repetitive transcranial magnetic stimulation (rTMS) might have positive effects in enhancing cognition and improving clinical symptoms in patients with depression. This study will investigate the effect of rTMS on cognition and long-term outcomes (12 month) of bipolar patients.

Conditions

• Cognitive Impairment
• Relapse
• Bipolar Disorder

Interventions

Type	Name	Description
DEVICE	Repetitive Transcranial Magnetic Stimulation	Daily left DLPFC, at 110% motor threshold, with a frequency of 10 Hz. Stimulation will be applied in 3-second trains with a 15-second inter-train interval, for 50 trains per session
DEVICE	Sham repetitive transcranial magnetic stimulation	Sham Transcranial Magnetic Stimulation

Timeline

• Start date: 2017-07-10
• Primary completion: 2019-12-30
• Completion: 2019-12-30
• First posted: 2017-07-02
• Last updated: 2020-04-27

Locations

1 site across 1 country: China