NCT03174067

Buprenorphine in the Emergency Department

Buprenorphine in the Emergency Department: Buprenorphine Versus Clonidine for Opioid Withdrawal

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 26 (actual)
• Sponsor: St. Joseph's Health Centre Toronto · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Not accepted

Summary

This is a pilot randomized control trial randomizing patients presenting in opioid withdrawal to the emergency department to receive either one of clonidine (usual standard of care) or buprenorphine for their opioid withdrawal. Primary treatment outcome is attendance at a rapid access addiction medicine clinic within a few days of emergency room presentation. Secondary treatment outcome is treatment status with respect to opioid agonist treatment at one month post emergency room visit.

Conditions

• Opioid Withdrawal
• Opioid-use Disorder

Interventions

Type	Name	Description
DRUG	Buprenorphine	The participant receives buprenorphine
DRUG	Clonidine	The participant receives clonidine

Timeline

• Start date: 2013-03-01
• Primary completion: 2016-04-01
• Completion: 2016-11-01
• First posted: 2017-06-02
• Last updated: 2017-06-02

Regulatory

• FDA-regulated drug study