NCT03165578

Neural Correlates of Neurofeedback Training

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 210 (estimated)
• Sponsor: Frank Scharnowski · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The objective of the present study is to identify brain networks in patients that contribute to successfully learning self-regulation with real-time fMRI.

Detailed description

Neurofeedback has been established as a promising non-pharmacological therapeutic approach. However, patients differ in their ability to learn control over their own brain activity with neurofeedback. It is thus crucial to understand the brain networks that mediate learned self-regulation with real-time fMRI. The objective of the present study is thus to identify brain networks in patients that contribute to successfully learning self-regulation with real-time fMRI. To achieve this goal, patients suffering from depression, post-traumatic stress disorder, and nicotine addiction will be trained to improve their self-regulation skills using established real-time fMRI neurofeedback protocols.

Conditions

• Nicotine Dependence
• Depression
• PTSD

Interventions

Type	Name	Description
OTHER	Neurofeedback training	In a neurofeedback setting, brain activity is measured non-invasively, the brain imaging data is analyzed in real-time, and then feedback regarding the current level of brain activity is provided to the subject.
OTHER	Sham Feedback	Sham controlled neurofeedback training. Subjects in the sham control group will undergo the same procedure as subjects in the experimental group, but instead of being shown feedback derived from their own brain activity, they will be shown replayed feedback values from a randomly chosen subject of the experimental group.

Timeline

• Start date: 2017-05-01
• Primary completion: 2020-09-30
• Completion: 2020-09-30
• First posted: 2017-05-24
• Last updated: 2017-05-24

Locations

1 site across 1 country: Switzerland