NCT03112876

Sebum Collection and Skin Barrier Function Analysis

Sebum Collection for Analysis and Correlation to Sebum Production, Barrier Function, and With Cutaneous and Internal Inflammatory Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 41 (actual)
• Sponsor: University of California, Davis · Academic / Other
• Sex: All
• Age: 12 Years
• Healthy volunteers: Accepted

Summary

The goal is this study is to evaluate how the skin surface lipid composition is correlated with overall sebum production, barrier function, and inflammatory disease status. We hypothesize that there will be differences in the skin surface composition among subjects of various groups: 1. Young vs older healthy population 2. Atopic dermatitis vs Acne vs Healthy controls 3. Active smokers vs non-smoker controls

Detailed description

This study will be conducted through the use of painless tapes to collect lipid. These will be applied to the skin and removed. Secondly, the barrier function will be evaluated through the use of non-invasive painless devices that measure sebum, skin water loss, and skin hydration.

Conditions

• Smoking
• Acne
• Atopic Dermatitis
• Aging

Interventions

Type	Name	Description
OTHER	Skin Surface Lipid Collection and Skin Barrier Function	All five groups will undergo the same study intervention: skin surface lipid collection via tapes and skin barrier function evaluated with non-invasive painless devices.

Timeline

• Start date: 2014-06-27
• Primary completion: 2016-02-26
• Completion: 2016-02-26
• First posted: 2017-04-13
• Last updated: 2017-04-13

Locations

1 site across 1 country: United States