Clinical Trials Directory

Trials / Completed

CompletedNCT03088956

Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD)

A Study to Model Rates of Change on Neuropsychological Test Measures in Subjects Diagnosed With Behavioral Variant Frontotemporal Dementia and Healthy Subjects

Status
Completed
Phase
Study type
Observational
Enrollment
47 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Accepted

Summary

The objectives of the study are to; (1) estimate the change in disease -related cognitive decline over 1 year on a battery of cognitive tests administered to participants with early-stage symptomatic Behavioral Variant Frontotemporal Dementia (bvFTD) phenotypic variant; (2) identify the cognitive test or brief battery of cognitive tests which are the most sensitive to detect bvFTD progression; (3) determine the optimal schedule of administration of cognitive tests to detect bvFTD progression; (4) evaluate the relationship between cognitive tests and measures of behavior, function, caregiver's burden, quality of life (QOL); and (5) obtain blood samples for genetic and exploratory biomarkers correlations.

Conditions

Interventions

TypeNameDescription
OTHERAssessmentsCognitive, Behavioral and Functional as described in the Outcome Measures

Timeline

Start date
2018-01-19
Primary completion
2019-09-23
Completion
2019-09-23
First posted
2017-03-24
Last updated
2020-06-16

Locations

12 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT03088956. Inclusion in this directory is not an endorsement.