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UnknownNCT03088657

Design and Methods of the Mood Disorder Cohort Research Consortium (MDCRC) Study

Mood Disorder Cohort Research Consortium (MDCRC) in Korea

Status
Unknown
Phase
Study type
Observational
Enrollment
500 (estimated)
Sponsor
Korea University Anam Hospital · Academic / Other
Sex
All
Age
35 Years
Healthy volunteers
Not accepted

Summary

The Mood Disorder Cohort Research Consortium (MDCRC) study is designed as a naturalistic observational prospective cohort study for early-onset mood disorders (major depressive disorders, bipolar disorders type 1 and 2) in South Korea.

Detailed description

The Mood Disorder Cohort Research Consortium (MDCRC) study is designed as a naturalistic observational prospective cohort study for early-onset mood disorders (major depressive disorders, bipolar disorders type 1 and 2) in South Korea. The study subjects consist of two populations: 1) patients with mood disorders under 25 years old and 2) patients with mood disorders within 2 years of treatment under 35 years old. After successful screening, the subjects are evaluated using baseline assessments and serial follow-up assessments at 3-month intervals. Between the follow-up assessments, subjects are dictated to check their own daily mood status before bedtime using the eMood chart application or a paper mood diary. In addition, wearable activity tracker(Fitbit charge series) is applied for data collection such as activity, sleep, and heart rate during every moments. At the regular visits every 3 months, inter-visit assessments are evaluated based on daily mood charts and interviews with patients. In addition to the daily mood chart, sleep quality, inter-visit major and minor mood episodes, stressful life events, and medical usage pattern with medical expenses are also assessed. Genomic DNA from blood is obtained for genomic analyses. From the MDCRC study, the clinical course, prognosis, and related factors of early-onset mood disorders can be clarified. The MDCRC is also able to facilitate translational research for mood disorders and provide a resource for the convergence study of mood disorders.

Conditions

Timeline

Start date
2015-09-01
Primary completion
2022-07-01
Completion
2022-09-01
First posted
2017-03-23
Last updated
2019-02-27

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT03088657. Inclusion in this directory is not an endorsement.