NCT02971072

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 180 (estimated)
• Sponsor: University of Oregon · Academic / Other
• Sex: All
• Age: 21 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy. There are three specific aims: (1) determine the effect of acute pain relief on rotator cuff muscle activation in patients with rotator cuff tendinopathy, (2) determine the effect of exercise on rotator cuff muscle activation in patients with rotator cuff tendinopathy, and (3) compare rotator cuff muscle activation between patients with rotator cuff tendinopathy and healthy controls.

Detailed description

The long-term goal of our research agenda is to identify the mechanisms associated with rotator cuff tendinopathy (impingement syndrome) and subsequently evaluate novel treatment strategies that address these mechanisms. The objectives of this application are to study the muscle patterns in patients with rotator cuff tendinopathy as well as the effects of both pain and exercise on these patterns. Our first hypothesis is that pain relief from a shoulder injection will result in increased rotator cuff activity. Our second hypothesis is that patients with tendinopathy will demonstrate improved rotator cuff muscle activity following a six-week exercise program and that this improvement will be higher in patients that respond favorably to treatment. Our final hypothesis is that patients with cuff tendinopathy will show decreased rotator cuff activity compared to healthy subjects. The investigators plan on addressing these hypotheses using several novel techniques for muscle activity assessment.

Conditions

• Acute Pain
• Atrophic
• Goals
• Impairment
• Infiltration
• Injury
• Muscle Weakness
• Pain
• Pathology
• Shoulder Pain
• Syndrome
• Tendinopathy

Interventions

Type	Name	Description
PROCEDURE	Subacromial injection	A subacromial injection consisting up 6 cc 0.5% Marcaine with Epinephrine and 1 cc DepoMedrol will be administered.
OTHER	Physical Therapy	A standardized six-week exercise protocol supervised by a physical therapist

Timeline

• Start date: 2014-07-01
• Primary completion: 2021-04-01
• Completion: 2021-04-01
• First posted: 2016-11-22
• Last updated: 2022-09-13

Locations

1 site across 1 country: United States