NCT02845076

Weaning From Noninvasive Ventilation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 197 (actual)
• Sponsor: Baskent University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Noninvasive ventilation (NIV) weaning strategies differ considerably from one another. These strategies have yet not been compared to each other. Therefore, the investigators planned to perform a prospective, randomized, pilot study involving hypercapnic acute respiratory failure patients ready to be weaned off from NIV. The investigators are going to compare the success rate of NIV weaning and the duration of NIV after randomization between 3 NIV weaning methods: gradual decrease in duration of NIV or level of ventilator support, and abrupt discontinuation of NIV.

Conditions

• Hypercapnic Respiratory Failure
• Weaning Failure
• Noninvasive Ventilation

Interventions

Type	Name	Description
OTHER	Protocol for weaning of noninvasive ventilation	3 protocols for weaning of noninvasive ventilation will be compared

Timeline

• Start date: 2016-09-01
• Primary completion: 2020-03-01
• Completion: 2020-03-01
• First posted: 2016-07-27
• Last updated: 2020-07-10

Locations

8 sites across 2 countries: Italy, Turkey (Türkiye)