Clinical Trials Directory

Trials / Completed

CompletedNCT02670538

Study of the Efficacy of a Fixed-dose Regimen of Cariprazine Compared to Placebo for Treatment of the Depressive Episode in Participants With Bipolar I Disorder

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Fixed-Dose Clinical Trial Evaluating The Efficacy, Safety And Tolerability Of Cariprazine In Patients With Bipolar I Depression

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
493 (actual)
Sponsor
Forest Laboratories · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

This study is designed to prospectively confirm the efficacy of a fixed-dose regimen of cariprazine 1.5 milligrams (mg)/day or 3 mg/day compared to placebo for treatment of the depressive episode in participants with bipolar I disorder. The safety and tolerability of the fixed-dose regimens will be evaluated.

Conditions

Interventions

TypeNameDescription
DRUGCariprazineCariprazine capsule one per day orally.
DRUGPlaceboMatching placebo capsule one per day orally.

Timeline

Start date
2016-03-31
Primary completion
2018-01-18
Completion
2018-01-18
First posted
2016-02-01
Last updated
2019-03-12
Results posted
2019-02-05

Locations

89 sites across 8 countries: United States, Bulgaria, Croatia, Puerto Rico, Romania, Serbia, Slovakia, Ukraine

Source: ClinicalTrials.gov record NCT02670538. Inclusion in this directory is not an endorsement.

Study of the Efficacy of a Fixed-dose Regimen of Cariprazine Compared to Placebo for Treatment of the Depressive Episode (NCT02670538) · Clinical Trials Directory