NCT02083406

Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP)

Open Label Study to Investigate the Pharmacokinetics of Prototype Formulations of OZ439 Administered With Piperaquine Phosphate in the Fasted State to Healthy Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Medicines for Malaria Venture · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

A single dose study to investigate how different formulations of OZ439 co-administered with PQP tablest are processed by the body when taken without food

Conditions

• Malaria

Interventions

Type	Name	Description
DRUG	800mg OZ439 prototype formulation 1
DRUG	800mg OZ439 prototype formulation 2
DRUG	800mg OZ439 prototype formulation 3
DRUG	960mg PQP

Timeline

• Start date: 2014-07-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2014-03-11
• Last updated: 2015-03-23
• Results posted: 2015-03-23

Locations

1 site across 1 country: United Kingdom