NCT02056353

Multicentre LOGIC-Insulin Algorithm-guided Versus Nurse-directed Blood Glucose Control During Critical Illness (LOGIC-2)

LOGIC-Insulin Computerized Algorithm-guided Versus Nurse-directed Blood Glucose Control in Critically Ill Patients: the LOGIC-2 Multicentre Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,550 (actual)
• Sponsor: KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Most critically ill patients are confronted with hyperglycaemia, which is associated with an increased mortality and morbidity risk. Normalising these elevated blood glucose levels by intensive insulin therapy may improve patient outcome, but is associated with an increased risk of hypoglycaemia. The LOGIC-2 study hypothesises that the LOGIC-Insulin computerised software algorithm will allow better (less hyperglycaemia) and safer (less hypoglycaemia) blood glucose control in critically ill patients than nurse-directed blood glucose control.

Conditions

• Critical Illness
• Hyperglycemia
• Hypoglycemia

Interventions

Type	Name	Description
DEVICE	LOGIC-Insulin algorithm
DEVICE	Paper protocol

Timeline

• Start date: 2014-02-01
• Primary completion: 2015-04-01
• Completion: 2015-08-01
• First posted: 2014-02-06
• Last updated: 2016-01-08

Locations

4 sites across 2 countries: Belgium, Netherlands