NCT01607723

"NAVA-PAV" Study: a Cross-over Comparative Study of 2 Advanced Modes

Comparison of Two New Ventilatory Modes: NAVA vs PAV+: a Randomized Controlled Cross-over Study: the "NAVA-PAV" Study

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: University Hospital, Montpellier · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Neurally adjusted ventilatory assist (NAVA) and Proportional Assist Ventilatory Plus (PAV +) are new modes of mechanical ventilation that delivers ventilatory assist in proportion to the electrical activity of the diaphragm for NAVA and to patients efforts for PAV +. The goal of this trial is to compare oxygenation,ventilator comfort, patients -ventilator asynchronies, and sleep pattern between NAVA and PAV+.

Detailed description

Twenty patients will be enrolled. They will be ventilated with PAV+ and NAVA for one day, each in a randomized crossover order. The oxygenation,ventilator comfort, patients -ventilator asynchronies, and sleep pattern will be compared.

Conditions

• Critical Illness
• Mechanical Ventilation
• Intensive Care
• Ventilation Weaning

Interventions

Type	Name	Description
OTHER	NAVA ventilatory mode	The two ventilatory modes will be studied during 24h in intubated patients in random order.
OTHER	PAV+ ventilatory mode	The two ventilatory modes will be studied during 24h in intubated patients in random order.

Timeline

• Start date: 2012-05-01
• Primary completion: 2012-05-01
• Completion: 2014-03-01
• First posted: 2012-05-30
• Last updated: 2014-12-03

Locations

1 site across 1 country: France