NCT01519297

Preeclampsia: A Marker for Future Cardiovascular Risk in Women

• Status: Suspended
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Brigham and Women's Hospital · Academic / Other
• Sex: Female
• Age: 21 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This study will compare blood vessel and hormone differences between women who have a history of a pregnancy complicated by preeclampsia or high blood pressure, and women who have a history of uncomplicated pregnancy in the last 10 years. The investigators hypothesize that postpartum women with history of preeclampsia will have altered blood vessel function and abnormal hormone levels compared with postpartum women with history of uncomplicated pregnancy. This study will take place over the course of 2 weeks. Each subject will be assessed on a fixed low-salt diet and a fixed high-salt diet. Subjects will have 2 non-invasive blood vessel imaging tests and fasting blood draws.

Conditions

• Preeclampsia
• Pregnancy Induced Hypertension

Interventions

Type	Name	Description
DRUG	Irbesartan	150mg orally for one dose

Timeline

• Start date: 2012-05-01
• Primary completion: 2017-07-01
• Completion: 2019-07-01
• First posted: 2012-01-26
• Last updated: 2019-01-17

Locations

1 site across 1 country: United States