NCT01377051

Effect of Indacaterol Maleate in Chronic Obstructive Pulmonary Disease (COPD) on Lung Volume and Related Dyspnea

Acute Effect of Indacaterol Maleate on Static and Dynamic Lung Volume in COPD Subjects.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: University of Milan · Academic / Other
• Sex: All
• Age: 50 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether indacaterol maleate 300 micrograms (mcg) is effective in the acute treatment of COPD and in particular on reducing lung hyperinflation and dynamic volumes.

Detailed description

Enrolled patients: COPD of any disease severity in stable conditions. 48 hours of inhalatory drugs wash out. Evaluation: Plethysmographic test, blood gas analysis, blood pressure, cardiac frequency and Borg scale evaluation in basal condition and after 60 minutes of indacaterol maleate 300 mcg inhalation.

Conditions

• COPD
• Lung Diseases
• Dyspnea
• Hypoxemia
• Tachycardia

Interventions

Type	Name	Description
DRUG	Indacaterol maleate	Dry powered, 300 mcg, only one inhalation with 24 hours duration
DRUG	Placebo	Dry powered, same to study drug, only one inhalation

Timeline

• Start date: 2011-05-01
• Primary completion: 2011-08-01
• Completion: 2011-09-01
• First posted: 2011-06-20
• Last updated: 2014-10-29

Locations

1 site across 1 country: Italy