NCT01265121

Sleep Apnea Syndrome on Acromegaly: Impact of the Treatment on the Carbohydrates Metabolism.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (estimated)
• Sponsor: University of Sao Paulo General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Sleep apnea is a common situation that affects up to 80% of acromegalic patients. This disease is linked to disturbance on the carbohydrate metabolism increasing the rates of diabetes. The objective of this trial is to assess (with the euglycemic hyperinsulinemic clamp) the impact of the treatment of sleep apnea, with a continuous positive air pressure device (CPAP), on the insulin resistance.

Conditions

• Acromegaly
• Obstructive Sleep Apnea
• Insulin Resistance

Interventions

Type	Name	Description
DEVICE	Continuous positive air pressure device (CPAP)	After titrating the air pressure during a polysomnography test, a CPAP device will be applied to the patient, during the night, for three months.
OTHER	External nasal dilator adhesive	An external nasal dilator adhesive will be given to patients. They will be applied on the nose and will be used for three months aiming to serve as a placebo for snoring and sleep apnea.

Timeline

• Start date: 2009-09-01
• Primary completion: 2011-04-01
• Completion: 2011-06-01
• First posted: 2010-12-22
• Last updated: 2010-12-22

Locations

1 site across 1 country: Brazil