NCT01262092

Effects of Gabapentin Versus Placebo on Buprenorphine Detoxification of Opioid-dependent Individuals

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: University of Arkansas · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study involves inducting treatment seeking opioid dependent participants onto buprenorphine. Once the participant reaches a stable dose they will receive either placebo or gabapentin to determine if gabapentin helps ease withdrawal symptoms while the participant undergoes a 10-day buprenorphine detoxification.

Conditions

• Opioid Dependence
• Opioid Withdrawal
• Opioid Detoxification

Interventions

Type	Name	Description
DRUG	Buprenorphine	Induction onto buprenorphine to a stable dose of 12mg/day. Then induction onto either 0 or 1600mg of gabapentin. Once the maintenance dose of gabapentin is reached a 10-day buprenorphine detoxification will begin.

Timeline

• Start date: 2010-10-01
• Primary completion: 2011-12-01
• Completion: 2012-01-01
• First posted: 2010-12-17
• Last updated: 2013-06-21
• Results posted: 2013-06-21

Locations

1 site across 1 country: United States