Clinical Trials Directory

Trials / Completed

CompletedNCT01198912

Influence of Oral Doxycycline on Wound Healing After Endonasal Endoscopic Sinus Surgery for Chronic Rhinosinusitis With and Without Nasal Polyposis: a Double-blind Randomized Placebo-controlled Trial

Influence of Oral Doxycycline on Wound Healing After Endonasal Endoscopic Sinus Surgery for Chronic Rhinosinusitis With and Without Nasal Polyposis: a Double-blind Randomized Placebo-controlled Trial.

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
33 (actual)
Sponsor
University Hospital, Ghent · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a randomized, double blind, placebo controlled, parallel group, study in patients with chronic rhinosinusitis with or without nasal polyps. The objective is to test the clinical efficacy of long-term low dose oral doxycycline on wound healing quality after endoscopic sinus surgery.

Conditions

Interventions

TypeNameDescription
DRUGplaceboduring 56 days
DRUGdoxycycline 100 mgduring 56 days

Timeline

Start date
2011-11-22
Primary completion
2016-09-06
Completion
2017-02-06
First posted
2010-09-10
Last updated
2018-06-15

Locations

2 sites across 2 countries: Belgium, Germany

Source: ClinicalTrials.gov record NCT01198912. Inclusion in this directory is not an endorsement.