NCT01178242

Salivary Gland Transplantation in the Treatment of Dry Eye in Patients With Stevens-Johnson Syndrome.

Salivary Gland and Labial Mucous Membrane Transplantation in the Treatment of Severe Symblepharon and Dry Eye in Patients With Stevens-Johnson Syndrome.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 19 (actual)
• Sponsor: Federal University of São Paulo · Academic / Other
• Sex: All
• Age: 10 Years – 58 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate salivary gland and labial mucous membrane transplantation in patients with severe symblepharon and dry eye secondary to Stevens-Johnson Syndrome (SJS).

Detailed description

This study was performed to evaluate the use of salivary gland and labial mucous membrane transplantation in patients with severe symblepharon and dry eye secondary to SJS. Labial mucous membrane and salivary gland transplantation showed to be a good option in the treatment of severe symblepharon and dry eye secondary to SJS. labial mucous membrane, salivary glands, symblepharon, entropion, transplantation, graft.

Conditions

• Symblepharon
• Dry Eye
• Ocular Surface Disease
• Transplantation

Interventions

Type	Name	Description
PROCEDURE	Salivary Gland and Labial Mucous Membrane Transplantation	Minor salivary glands (SG) will be obtain "en block" from the same donor site, at the inferior or superior labial mucous membrane, above the orbicularis oris muscle to correct lubrication. The thin split thickness graft of mucous membrane will be suture to the sclera with absorbable sutures

Timeline

• Start date: 2008-12-01
• Primary completion: 2010-04-01
• Completion: 2010-12-01
• First posted: 2010-08-10
• Last updated: 2016-08-11

Locations

1 site across 1 country: Brazil