Clinical Trials Directory

Trials / Completed

CompletedNCT01032044

CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia

Confocal Laser Endomicroscopy for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
164 (actual)
Sponsor
Mauna Kea Technologies · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study focuses on demonstrating the value of probe-based Confocal Laser Endomicroscopy (pCLE) in guiding endoscopic therapeutic procedures in Barrett's Esophagus (BE). It is a randomized controlled outcomes study including patients already treated for Barrett's Esophagus lesion(s) and undergoing high definition white light endoscopy follow up procedure, with or without pCLE (2 arms will be considered in this study). The procedures will be carried out per standards of practice with appropriately trained physicians.

Detailed description

It is a randomized controlled outcomes study including patients already treated for Barrett's Esophagus lesion(s) and undergoing high definition white light endoscopy follow up procedure, with or without pCLE guided evaluation (2 arms will be considered in this study). The procedures will be carried out per standards of practice with appropriately trained physicians.

Conditions

Interventions

TypeNameDescription
DEVICEStandard endoscopic evaluationTreatment modalities can include endoscopic mucosal resection, radio-frequency ablation or photodynamic therapy
DEVICEpCLE guided evaluationTreatment modalities include endoscopic mucosal resection, radio-frequency ablation, or photodynamic therapy. probe-based Confocal Laser Endomicroscopy is used to decide on re-treatment or not, and to guide and evaluate the treatment during the same endoscopic procedure.

Timeline

Start date
2010-02-01
Primary completion
2011-04-01
Completion
2011-04-01
First posted
2009-12-15
Last updated
2016-04-22
Results posted
2016-04-22

Locations

6 sites across 3 countries: United States, France, United Kingdom

Source: ClinicalTrials.gov record NCT01032044. Inclusion in this directory is not an endorsement.