NCT00930085

Evaluation of Predictive Proteic Profile on Mortality in the Acute Phase of Septic Shock in Cancer Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Institut Paoli-Calmettes · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The mortality induced by infections in onco-hematological patients is abnormally high at the acute phase of septic shock. Consequently, it is important to detect the population with a high risk of short term mortality among patients with a septic shock. The aim of this study is the evaluation of predictive proteic profile on the short term mortality in the acute phase of septic shock in cancer patients.

Detailed description

Method: Monocentric prospective study with diagnostic and prognostic expectations. Primary objective: Identification and characterization of early proteic biomarkers predictive of short term mortality in cancer patients with septic shock. Secondary objective: Research of clinical and biological prognostic factors.

Conditions

• Sepsis
• Septic Shock
• Cancer

Interventions

Type	Name	Description
OTHER	SELDI-TOF MS for plasmatic proteic profile	An extra blood sample is required to determine the plasmatic proteic profile used to identify one or several signatures which are correlated to the clinical evolution (mortality at D30).

Timeline

• Start date: 2008-08-01
• Primary completion: 2011-04-01
• Completion: 2011-05-01
• First posted: 2009-06-30
• Last updated: 2011-09-14

Locations

1 site across 1 country: France