NCT00835913

Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis Impact

Autonomic Nervous System Alteration Induce by Sepsis:Assessment and Prognosis Impact

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 13 (actual)
• Sponsor: University Hospital, Grenoble · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Severe sepsis and septic shock are causes of admission in intensive care units.Modification of natriuretic peptid including NT-proBNP and cardiac autonomic nervous system alteration are reported in sepsis shock and severe sepsis and seems to link to patient prognosis admitted to intensive care units.

Detailed description

Our principal aim is to characterize modulation of cardiac sympathic nervous system in sepsis through the study of sinusal change and myocardiac fixing of MIBG. The second aim is 1)to assess links between alteration of cardiac sympathic nervous system and NT-PRoBNP variations in sepsis and 2)To know prognostic impact in sympathic nervous system compare to NTproBNP.

Conditions

• Septic Shock
• Severe Sepsis

Timeline

• Start date: 2008-10-01
• Primary completion: 2011-09-01
• Completion: 2011-09-01
• First posted: 2009-02-04
• Last updated: 2015-01-19

Locations

1 site across 1 country: France