Trials / Terminated
TerminatedNCT00752271
AMS Study: Inflammatory and Biomechanical Contributors to Arthritis Development Following Arthroscopic Meniscectomy
Inflammatory and Biomechanical Contributors to Arthritis Development Following Arthroscopic Meniscectomy
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 32 (estimated)
- Sponsor
- National Institute on Aging (NIA) · NIH
- Sex
- All
- Age
- 40 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to examine the relationship between muscle activation and heart rate on joint generalized inflammation and arthritis development.
Detailed description
This study will test the hypothesis that knee trauma (as exemplified by the arthroscopy procedure) causes inflammation that alters muscle activation patterns locally and also disrupts the balance between parasympathetic-sympathetic reflexes. It is hypothesized that these factors contribute to development and progression of knee osteoarthritis.
Conditions
Timeline
- Start date
- 2008-05-01
- Primary completion
- 2010-05-01
- Completion
- 2010-05-01
- First posted
- 2008-09-15
- Last updated
- 2009-12-18
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00752271. Inclusion in this directory is not an endorsement.