NCT00730054

Clonidine-Remifentanil. Effect of the Combination on Acute Pain and Respiration in Healthy Volunteers

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Oslo University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The hypothesis is that systemic remifentanil and Clonidine act in a synergistic manner to relief acute main in an experimental human pain model. Of interest is also the effect of the combination on respiration, sedation and cognitive behavior.

Detailed description

To examine the possible synergistic effects og systemic remifentanil and clonidine. Its effects on respiration, cognitive function and sedation.

Conditions

• Acute Pain
• Respiration
• Sedation

Interventions

Type	Name	Description
DRUG	Remifentanil+clonidine	iv Remifentanil+ iv clonidine

Timeline

• Start date: 2005-02-01
• Primary completion: 2005-05-01
• Completion: 2005-05-01
• First posted: 2008-08-08
• Last updated: 2011-07-06

Locations

1 site across 1 country: Norway