Trials / Completed
CompletedNCT00588640
Study of D-Methadone in Patients With Chronic Pain
A Phase I/II Study of D-Methadone in Patients With Chronic Pain
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 10 (actual)
- Sponsor
- Memorial Sloan Kettering Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine the safest dose of d-methadone that can be given, without causing severe side effects in most patients with chronic pain. Patients are being asked to participate in the Phase I portion of this study.
Conditions
- Pain
- Bladder Cancer
- Breast Cancer
- CNS Cancer
- Colon Cancer
- Esophageal Cancer
- Pancreatic Cancer
- Prostate Cancer
- Uterine Cancer
- Head and Neck Cancer
- Eye Cancer
- Otorhinolaryngologic Neoplasms
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | d-Methadone | 8 subjects to receive 40 mg d-Methadone twice a day |
| DRUG | D-methadone | After randomization, patients will take the study drug or placebo for 12 days and then they will cross-over to the opposite arm for another 12 days. The study will end on day 24. |
| DRUG | placebo | After randomization, patients will take the study drug or placebo for 12 days and then they will cross-over to the opposite arm for another 12 days. The study will end on day 24. |
Timeline
- Start date
- 2004-10-01
- Primary completion
- 2008-07-01
- Completion
- 2008-07-01
- First posted
- 2008-01-08
- Last updated
- 2016-08-10
- Results posted
- 2016-08-10
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00588640. Inclusion in this directory is not an endorsement.