Clinical Trials Directory

Trials / Completed

CompletedNCT00523341

Extension Study to Evaluate the Long Term Safety and Efficacy of Denosumab in the Treatment of Osteoporosis

An Open Label, Single Arm, Extension Study to Evaluate the Long Term Safety and Sustained Efficacy of Denosumab (AMG162) in the Treatment of Postmenopausal Osteoporosis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
4,550 (actual)
Sponsor
Amgen · Industry
Sex
Female
Age
60 Years – 94 Years
Healthy volunteers
Not accepted

Summary

The primary objective was to describe the safety and tolerability of up to 10 years or 7 years denosumab administration as measured by adverse event monitoring, immunogenicity and safety laboratory parameters in participants who previously received denosumab or placebo, respectively.

Conditions

Interventions

TypeNameDescription
BIOLOGICALDenosumabAdministered by subcutaneous injection once every 6 months.

Timeline

Start date
2007-08-07
Primary completion
2015-07-19
Completion
2015-07-19
First posted
2007-08-31
Last updated
2022-11-07
Results posted
2016-07-12

Source: ClinicalTrials.gov record NCT00523341. Inclusion in this directory is not an endorsement.