NCT00245427

Outcomes of Patients Not Responding to Antibiotics in the Community

Outcomes of Patients Not Responding to Outpatient Macrolide or b-Lactam Therapy for the Treatment of Community Acquired Pneumonia: Expansion to Include Acute Exacerbations of Chronic Bronchitis and Acute Sinusitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: CPL Associates · Academic / Other
• Sex: All
• Age: 95 Years
• Healthy volunteers: Not accepted

Summary

A study to report the outcomes of patients who fail to respond to beta-lactam and macrolide antibiotics in the community

Detailed description

To document and describe the clinical, microbiological, and pharmacoeconomic outcomes of two hundred patients who failed to respond to outpatient macrolide or beta-lactam therapy. Evaluable patients must have a positive culture obtained after they failed their initial macrolide or beta-lactam. The isolated pathogen must have a known MIC to the antibiotic class they failed to respond to (i.e. macrolide or b-lactam). The isolate must be available to be sent to the central laboratory for MIC testing

Conditions

• Sinusitis
• Bronchitis, Chronic
• Pneumonia, Bacterial

Interventions

Type	Name	Description
DRUG	all macrolide antibiotics	Varies based on antibiotic
DRUG	all beta-lactam antibiotics	Varies based on antibiotic

Timeline

• Start date: 2005-12-01
• Completion: 2006-03-01
• First posted: 2005-10-28
• Last updated: 2007-10-31

Locations

1 site across 1 country: United States