Clinical Trials Directory

Trials / Completed

CompletedNCT00004771

Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
40 (planned)
Sponsor
National Center for Research Resources (NCRR) · NIH
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

OBJECTIVES: I. Evaluate the effects of androgen suppression with leuprolide and androgen replacement with testosterone enanthate on muscle strength in men with Kennedy's disease or other motor neuron disease.

Detailed description

PROTOCOL OUTLINE: All patients receive androgen suppression with leuprolide acetate injections every 4 weeks for 6 months, plus hormone replacement therapy with testosterone enanthate injections every week for 24 weeks.

Conditions

Interventions

TypeNameDescription
DRUGleuprolide
DRUGtestosterone

Timeline

Start date
1992-10-01
First posted
2000-02-25
Last updated
2005-06-24

Source: ClinicalTrials.gov record NCT00004771. Inclusion in this directory is not an endorsement.