| Not Yet Recruiting | Decreasing Edema With a Novel OCS Solution Trial Lung Transplant | N/A | 2026-03-01 |
| Recruiting | Enhancing Heart Allograft Function With the OCS Heart System Trial Heart Transplant | N/A | 2026-01-01 |
| Recruiting | US National TOP Registry Lung Transplant | — | 2025-01-23 |
| Recruiting | US National OCS Heart Perfusion (OHP) Registry Heart Transplant | — | 2023-08-25 |
| Active Not Recruiting | OCS Liver Perfusion (OLP) Post-Approval Registry Liver Transplant | — | 2021-10-14 |
| Recruiting | US National OCS Liver Perfusion (OLP) Registry Liver Transplant | — | 2021-10-14 |
| Active Not Recruiting | OCS Heart Perfusion Post-Approval Registry Transplant | — | 2021-09-13 |
| Completed | Donor After Circulatory Death Heart CAP Trial Heart Transplant | N/A | 2020-11-25 |
| Terminated | OCS Liver DCD Trial Liver Transplant | N/A | 2020-07-24 |
| Completed | OCS Liver PROTECT Continued Access Protocol (CAP) Continuation Post-Approval Study Liver Transplant | — | 2020-02-03 |
| Completed | OCS Liver PROTECT Continued Access Protocol Liver Transplant | N/A | 2020-02-03 |
| Active Not Recruiting | OCS DCD Heart + CAP Continued Follow-Up Heart Transplant | — | 2019-11-26 |
| Completed | Donors After Circulatory Death Heart Trial Heart Transplant | N/A | 2019-11-26 |
| Completed | INSPIRE Continuation Post-Approval Study Bronchiolitis Obliterans | — | 2019-06-30 |
| Completed | Heart EXPAND Continued Access Protocol Heart Transplant | N/A | 2019-04-17 |
| Completed | OCS Lung Expand Post-Approval Study - Expand Follow-Up Data Collection OCS Lung System | — | 2018-12-31 |
| Active Not Recruiting | OCS™ Lung TOP Registry For Donor Lungs for Transplantation Lung Transplantation | — | 2018-12-10 |
| Terminated | OCS Lung System EXPAND II Trial Lung Transplantation | N/A | 2018-03-12 |
| Completed | Trial of the TransMedics Organ Care System™ Liver For Preserving and Assessing Donor Livers for Transplantatio Liver Preservation | N/A | 2016-05-01 |
| Completed | OCS Liver PROTECT Trial: Preserving and Assessing Donor Livers for Transplantation Liver Transplantation, Liver Preservation for Transplant | N/A | 2016-01-24 |
| Completed | OCS Liver PROTECT Continuation Post-Approval Study Liver Transplant | — | 2016-01-24 |
| Active Not Recruiting | OCS Heart EXPAND + CAP Continued Follow-Up Heart Transplant | — | 2015-09-16 |
| Completed | International EXPAND Heart Pivotal Trial Heart Transplant | N/A | 2015-09-16 |
| Completed | International EXPAND Lung Pivotal Trial Lung Transplant | N/A | 2013-11-01 |
| Completed | International Randomized Study of the TransMedics Organ Care System (OCS Lung) for Lung Preservation and Trans Lung Preservation | N/A | 2011-11-01 |
| Completed | Randomized Study of Organ Care System Cardiac for Preservation of Donated Hearts for Eventual Transplantation Heart Failure | N/A | 2009-03-01 |