Clinical Trials Directory

Trials / Terminated

TerminatedNCT03343535

OCS Lung System EXPAND II Trial

Trial to Evaluate the Safety and Effectiveness of the Portable Organ Care System (OCS™) Lung System for Recruiting, Preserving and Assessing Non-Ideal Donor Lungs for Transplantation

Status
Terminated
Phase
N/A
Study type
Interventional
Enrollment
46 (actual)
Sponsor
TransMedics · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

To evaluate the safety and effectiveness of the OCS™ Lung System to recruit, preserve and assess non-ideal donor lungs that may not meet current standard donor lung acceptance criteria for transplantation.

Detailed description

Inclusion At least one of the following: * Donor PaO2/FiO2 ≤ 300 mmHg at the time of the offer; or * Expected cross-clamp time \> 6 hours for the second lung; or * Donor after Cardiac Death (DCD donor); or * Donor age ≥ 55 years old

Conditions

Interventions

TypeNameDescription
DEVICEOCS Lung PreservationOCS Lung Preservation

Timeline

Start date
2018-03-12
Primary completion
2019-08-27
Completion
2022-07-06
First posted
2017-11-17
Last updated
2024-02-28
Results posted
2024-02-28

Locations

14 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03343535. Inclusion in this directory is not an endorsement.