Clinical Trials Directory

Trials / Completed

CompletedNCT03835754

Heart EXPAND Continued Access Protocol

Heart Expand Continued Access Protocol

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
75 (actual)
Sponsor
TransMedics · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The OCS™ Heart System will be used to preserve and assess donor hearts that do not meet current standard donor heart acceptance criteria for transplantation in this continued access protocol.

Detailed description

To provide additional data evaluating the safety and effectiveness of the OCS™ Heart System to preserve and assess donor hearts that do not meet current standard donor heart acceptance criteria (as identified above) for transplantation to potentially improve donor heart utilization for transplantation at a range of transplant centers in the U.S. and to permit patients and physicians access to the OCS Heart System while a PMA application is under preparation and review.

Conditions

Interventions

TypeNameDescription
DEVICEOCS Heart SystemThe OCS Heart System preserves the heart in a near-physiological, beating state by perfusing the heart with a warmed, donor-blood based perfusate that is supplemented with nutrients and oxygen in a controlled and protected environment

Timeline

Start date
2019-04-17
Primary completion
2021-09-15
Completion
2022-08-12
First posted
2019-02-11
Last updated
2025-01-17
Results posted
2025-01-17

Locations

12 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03835754. Inclusion in this directory is not an endorsement.