Clinical Trials Directory

Trials / Sponsors / ModernaTX, Inc.

ModernaTX, Inc.

Industry · 110 registered clinical trials13 currently recruiting.

StatusTrialPhaseStarted
RecruitingA Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults
Influenza
Phase 32026-03-23
RecruitingA Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189 in Healthy Adults 18 to 30 Years of Age
Epstein-Barr Virus
Phase 12026-03-17
RecruitingA Study to Evaluate the Efficacy and Safety of mRNA-1283 and mRNA-1273 in Participants 50 to 64 Years of Age W
SARS-CoV-2
Phase 42025-11-26
RecruitingA Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma
Relapsed or Refractory Multiple Myeloma
Phase 1 / Phase 22025-09-30
Active Not RecruitingA Study of mRNA-1345 Following a Primary Dose of a Licensed Protein Subunit Respiratory Syncytial Virus (RSV)
Respiratory Syncytial Virus
Phase 32025-08-05
RecruitingA Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Variant-containing Formulations
COVID-19
Phase 42025-07-21
RecruitingA Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participa
Multiple Sclerosis
Phase 22025-04-16
Active Not RecruitingA Study of mRNA-4106 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants Wit
Advanced Solid Tumors
Phase 12025-03-25
CompletedA Study to Investigate the Immunogenicity, Reactogenicity, and Safety of mRNA-1083 (Influenza and COVID-19) Va
Influenza, SARS-CoV-2
Phase 22025-03-07
CompletedStudy to Investigate the Immunogenicity, Reactogenicity, and Safety of mRNA-1083 Vaccine (SARS-CoV-2 [COVID-19
COVID-19, Influenza
Phase 32024-11-18
Active Not RecruitingA Study to Investigate Safety and Tolerability of mRNA-0184 Administered Subcutaneously in Healthy Participant
Healthy Participants
Phase 12024-10-31
CompletedA Study to Investigate Cardiac Troponin Levels After mRNA-1273.712 Vaccine in Participants 12 Through 30 Years
Healthy Volunteers
Phase 42024-10-08
Active Not RecruitingA Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of Age for the Preventio
Acute Gastroenteritis, Norovirus Acute Gastroenteritis
Phase 32024-09-24
CompletedA Study of mRNA-1010 Compared With a Licensed Influenza Vaccine in Adults ≥50 Years of Age
Seasonal Influenza
Phase 32024-09-16
RecruitingA Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Vaccine Formulations
SARS-CoV-2
Phase 42024-09-09
CompletedA Clinical Study to Investigate the Safety and Immunogenicity in Relation to Product Attributes of mRNA-1083 (
Influenza, SARS-CoV-2
Phase 22024-07-15
CompletedA Study of an Investigational mRNA-1273.815 COVID-19 Vaccine in Previously Vaccinated Adults
SARS-CoV-2
Phase 32024-04-08
WithdrawnA Dose-finding Study to Evaluate mRNA-3210 in Participants With Phenylketonuria
Phenylketonuria
Phase 1 / Phase 22024-03-29
CompletedStudy to Investigate Safety and Tolerability of mRNA-0184 Administered Under Different Infusion Conditions in
Healthy Participants
Phase 12024-02-16
WithdrawnA Study of mRNA-1647 Cytomegalovirus Vaccine in Liver Transplant Candidates and Recipients
Cytomegalovirus Infection
Phase 22024-02-08
Active Not RecruitingA Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus in Pregnant Women and in Infants Born to Va
Respiratory Syncytial Virus
Phase 22023-11-15
CompletedA Study of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in Children 2 to <18 Years of Age
Respiratory Syncytial Virus
Phase 22023-10-24
CompletedA Study of mRNA-1083 (SARS-CoV-2 and Influenza) Vaccine in Healthy Adult Participants, ≥50 Years of Age
SARS-CoV-2, Influenza
Phase 32023-10-19
Active Not RecruitingA Study to Investigate the Immunogenicity and Safety of mRNA-1345 Vaccine Targeting Respiratory Syncytial Viru
Respiratory Syncytial Virus
Phase 32023-10-06
CompletedA Study to Evaluate the Safety and Immune Response of mRNA-1345, a Vaccine Targeting Respiratory Syncytial Vir
Respiratory Syncytial Virus
Phase 32023-09-25
CompletedA Study of mRNA-1608, a Herpes Simplex Virus -2 (HSV-2) Therapeutic Candidate Vaccine, in Healthy Adults 18 to
Genital Herpes
Phase 1 / Phase 22023-09-06
Active Not RecruitingStudy to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1403 and mRNA-1405 to Prevent Norovir
Norovirus Acute Gastroenteritis
Phase 1 / Phase 22023-08-25
CompletedA Study to Investigate The Safety, Tolerability, And Immune Response of a Range of Doses of mRNA-1769 Compared
Smallpox, Mpox
Phase 1 / Phase 22023-08-15
WithdrawnmRNA-2736 for Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Relapsed or Refractory Multiple Myeloma
Phase 12023-08-15
CompletedA Study to Evaluate the Safety and Immunogenicity of mRNA-1975 and mRNA-1982 Against Lyme Disease in Participa
Lyme Disease
Phase 1 / Phase 22023-07-26
CompletedA Study of mRNA-1018 Pandemic Influenza Candidate Vaccines in Healthy Adults
Influenza
Phase 1 / Phase 22023-07-10
RecruitingA Retrospective Study to Characterize Participants With Propionic Acidemia
Propionic Acidemia
2023-06-16
CompletedStudy to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA Vaccine Candidate Variations in Healt
Influenza
Phase 22023-05-15
CompletedStudy of mRNA-1010 Seasonal Influenza Vaccine in Adults
Seasonal Influenza
Phase 32023-04-17
CompletedA Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults
SARS-CoV-2, Influenza
Phase 1 / Phase 22023-04-14
CompletedPost-marketing Safety of Elasomeran/Davesomeran and Andusomeran
SARS-CoV-2
2023-04-14
Active Not RecruitingA Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1195, in 18- to 55-Year-Old Healthy Participant
Epstein-Barr Virus Infection
Phase 12023-04-05
RecruitingA Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in All
Cytomegalovirus Infection
Phase 22023-04-05
CompletedA Study on the Clinical Course, Outcomes and Risk Factors of Myocarditis and Pericarditis After Moderna COVID-
Myocarditis, Pericarditis
2023-03-31
CompletedA Study of mRNA-1283 Injection Compared With mRNA-1273 Injection in Participants ≥12 Years of Age to Prevent C
COVID-19
Phase 32023-03-28
CompletedA Study of mRNA-1011.1, mRNA-1011.2, and mRNA-1012.1 Candidate Seasonal Influenza Vaccines in Healthy Adults
Seasonal Influenza
Phase 1 / Phase 22023-03-27
Active Not RecruitingPost-marketing Surveillance (PMS) Use-Result Surveillance With SPIKEVAX BIVALENT, SPIKEVAX X Injection, SPIKEV
SARS-CoV-2
2023-03-10
CompletedAn Observational Study of Moderna COVID-19 Bivalent Vaccines (Original and Omicron BA.4/BA.5) and 2023 Updated
COVID-19
2023-03-08
CompletedStudy to Assess Maternal and Infant Outcomes Following Exposure to SPIKEVAX During Pregnancy
Maternal Outcomes, Infant Outcomes, Pregnancy
2023-03-01
Active Not RecruitingA Safety, Tolerability, and Immunogenicity Study of mRNA-1345 and mRNA-1365 in Participants Aged 5 Months to <
Respiratory Syncytial Virus, Human Metapneumovirus
Phase 12023-02-15
Active Not RecruitingA Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of
Herpes Zoster
Phase 1 / Phase 22023-01-23
CompletedA Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure
Chronic Heart Failure
Phase 12022-12-05
CompletedPost-Marketing Non-Acute Safety Study in Japan After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV
SARS-CoV-2
2022-11-15
CompletedPost-Marketing Safety Study in Japan of Shock and Anaphylaxis After Severe Acute Respiratory Syndrome Coronavi
SARS-CoV-2
2022-11-15
CompletedPost-Marketing Safety Study in Japan in Participants With High Risk of Severe Exacerbation of Severe Acute Res
SARS-CoV-2
2022-11-15
Active Not RecruitingA Study of mRNA-1647 Cytomegalovirus Vaccine in Healthy Participants 9 to 15 Years of Age and Participants 16
Cytomegalovirus
Phase 1 / Phase 22022-11-07
CompletedA Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Adults
Influenza
Phase 22022-11-02
CompletedA Safety, Reactogenicity, and Immunogenicity Study of mRNA-1045 (Influenza and Respiratory Syncytial Virus [RS
SARS-CoV-2, Influenza, RSV
Phase 12022-10-14
TerminatedStudy to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273.214 SARS-CoV-2 (COVID-19) Vaccine
SARS-CoV-2
Phase 22022-09-30
CompletedModerna Vaccine mRNA-1345 Observational Respiratory Syncytial Virus (RSV) Study
Respiratory Syncytial Virus
2022-09-15
CompletedA Study of mRNA-1010 Seasonal Influenza Vaccine in Adults 50 Years Old and Older
Seasonal Influenza
Phase 32022-09-14
RecruitingStudy of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With
Advanced Solid Tumors
Phase 1 / Phase 22022-09-01
CompletedA Study to Evaluate the Safety and Immunogenicity of the mRNA COVID-19 Vaccines in Healthy Children Between 6
SARS-CoV-2
Phase 32022-06-21
CompletedUse of Wearable Digital Sensors After mRNA Vaccination in Adults
Healthy Participants
2022-06-16
CompletedA Study of mRNA-1010 Seasonal Influenza Vaccine in Adults
Seasonal Influenza
Phase 32022-06-06
Active Not RecruitingA Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease Type 1a (GSD1a)
Glycogen Storage Disease
Phase 1 / Phase 22022-06-01
CompletedA Study of Modified mRNA Vaccines in Healthy Adults
SARS-CoV-2, Seasonal Influenza, Respiratory Syncytial Virus
Phase 12022-05-24
CompletedA Safety, Reactogenicity, and Immunogenicity Study of mRNA-1073 (COVID-19/Influenza) Vaccine in Adults 18 to 7
SARS-CoV-2, Influenza
Phase 1 / Phase 22022-05-13
Active Not RecruitingA Study to Assess Long-term Outcomes of Myocarditis Following Administration of COVID-19 mRNA Vaccine (SPIKEVA
Myocarditis
2022-04-30
CompletedA Study to Determine Antibody Levels After Receiving COVID-19 Boosters of Any Kind
SARS-CoV-2
2022-04-11
CompletedA Study of mRNA-1020 and mRNA-1030 Seasonal Influenza Vaccines in Healthy Adults
Seasonal Influenza
Phase 1 / Phase 22022-04-06
CompletedA Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥50 Years of Age
Respiratory Syncytial Virus
Phase 32022-04-01
RecruitingAn Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previou
Methylmalonic Acidemia
Phase 1 / Phase 22022-03-08
CompletedA Study to Evaluate the Immunogenicity and Safety of Omicron Variant Vaccines in Comparison With mRNA-1273 Boo
SARS-CoV-2
Phase 2 / Phase 32022-02-16
Active Not RecruitingA Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents
Epstein-Barr Virus Infection
Phase 1 / Phase 22021-12-28
CompletedLong-Term Follow-up Survey of COVID-19 Vaccine After Vaccination
Coronavirus Disease (COVID-19)
2021-12-22
CompletedA Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Vaccine Boosters
SARS-CoV-2
Phase 22021-12-06
CompletedA Study to Evaluate the Safety and Efficacy of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) i
Respiratory Syncytial Virus
Phase 2 / Phase 32021-11-17
RecruitingA Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled
Propionic Acidemia
Phase 1 / Phase 22021-11-09
CompletedA Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647
Cytomegalovirus Infection
Phase 12021-11-08
TerminatedA Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Hea
Cytomegalovirus Infection
Phase 32021-10-26
CompletedA Study to Compare mRNA-1273 Versus BNT162b2 COVID-19 Vaccines Among Immunocompromised Adults
SARS-CoV-2
2021-09-10
TerminatedModerna COVID-19 Vaccine mRNA-1273 Observational Pregnancy Outcome Study
SARS-CoV-2
2021-09-01
Active Not RecruitingA Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of mRNA-3705 in Participants With Isolate
Methylmalonic Acidemia
Phase 1 / Phase 22021-08-06
CompletedA Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of mRNA-6231 in Healthy A
Healthy Volunteers
Phase 12021-07-28
CompletedPost-Marketing Safety Study of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA-1273 COVID-19
SARS-CoV-2
2021-07-07
CompletedA Study of mRNA-1010 Seasonal Influenza Vaccine in Healthy Adults
Seasonal Influenza
Phase 1 / Phase 22021-07-06
CompletedA Long-Term Extension Study to Evaluate the Immunogenicity and Safety of Cytomegalovirus (CMV) mRNA-1647 Vacci
Cytomegalovirus Infection
Phase 22021-06-18
CompletedA Study of Zika Vaccine mRNA-1893 in Adult Participants Living in Endemic and Non-Endemic Flavivirus Areas
Zika Virus
Phase 22021-06-07
CompletedA Study to Evaluate the Immunogenicity and Safety of mRNA Vaccine Boosters for SARS-CoV-2 (COVID-19) Variants
SARS-CoV-2
Phase 2 / Phase 32021-05-28
CompletedA Study to Evaluate Safety and Immunogenicity of mRNA-1273 Vaccine to Prevent COVID-19 in Adult Organ Transpla
SARS-CoV-2
Phase 32021-04-16
RecruitingOpen-Label Study of mRNA-3927 in Participants With Propionic Acidemia
Propionic Acidemia
Phase 1 / Phase 22021-04-15
CompletedA Study to Evaluate Safety and Effectiveness of mRNA-1273 COVID-19 Vaccine in Healthy Children Between 6 Month
SARS-CoV-2
Phase 2 / Phase 32021-03-15
CompletedA Study to Evaluate Safety, Reactogenicity, and Immunogenicity of mRNA-1283 and mRNA-1273 Vaccines in Healthy
SARS-CoV-2
Phase 12021-03-11
CompletedA Study of the Effectiveness of Moderna COVID-19 Vaccine
SARS-CoV-2, COVID-19
2020-12-18
CompletedA Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273 Vaccine in Adolescents 12 to <1
SARS-CoV-2
Phase 2 / Phase 32020-12-09
CompletedA Dose Escalation Study to Evaluate Safety, Reactogenicity, and Immunogenicity of mRNA-1345 in Healthy Adults
Respiratory Syncytial Virus
Phase 12020-09-30
CompletedA Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Olde
SARS-CoV-2
Phase 32020-07-27
CompletedDose-Confirmation Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1273 COVID-19 Vacci
SARS-CoV-2
Phase 22020-05-29
CompletedDose-Finding Trial to Evaluate the Safety and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647 in Hea
Cytomegalovirus Infection
Phase 22020-01-09
CompletedSafety and Immunogenicity of mRNA-1653, a Combined Human Metapneumovirus (hMPV) and Parainfluenza Virus Type 3
Human Metapneumovirus and Human Parainfluenza Infection
Phase 12019-11-04
CompletedSafety, Tolerability, and Immunogenicity of Zika Vaccine mRNA-1893 in Healthy Flavivirus Seropositive and Sero
Zika Virus
Phase 12019-07-30
Active Not RecruitingAn Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab in Pa
Melanoma
Phase 22019-07-18
WithdrawnOpen Label Study of mRNA-3704 in Patients With Isolated Methylmalonic Acidemia
Methylmalonic Acidemia (MMA), Metabolism, Inborn Errors
Phase 1 / Phase 22019-05-28
CompletedSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of mRNA-1944 in Healthy Adults
Prevention of Chikungunya Virus Infection
Phase 12019-01-22
CompletedDose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or Lymphoma, Dose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
Phase 12018-11-27
Completed"The MaP Study": Mapping the Patient Journey in MMA and PA
Methylmalonic Acidemia, Propionic Acidemia
2018-03-20
CompletedSafety, Reactogenicity, and Immunogenicity of mRNA-1653 in Healthy Adults
Human Metapneumovirus and Human Parainfluenza Infection
Phase 12017-12-04
CompletedSafety, Reactogenicity, and Immunogenicity of Cytomegalovirus Vaccines mRNA-1647 and mRNA-1443 in Healthy Adul
Cytomegalovirus Infection
Phase 12017-11-13
TerminatedDose Escalation and Efficacy Study of mRNA-2416 for Intratumoral Injection Alone and in Combination With Durva
Relapsed/Refractory Solid Tumor Malignancies or Lymphoma, Ovarian Cancer
Phase 1 / Phase 22017-08-15
Active Not RecruitingSafety, Tolerability, and Immunogenicity of mRNA-4157 Alone and in Combination in Participants With Solid Tumo
Solid Tumors
Phase 12017-08-14
CompletedSafety, Tolerability, and Immunogenicity of VAL-181388 in Healthy Participants
Chikungunya Virus
Phase 12017-07-19
CompletedSafety, Tolerability, and Immunogenicity of mRNA-1325 in Healthy Adult Subjects
Zika Virus
Phase 12016-12-21
CompletedSafety, Tolerability, and Immunogenicity of VAL-339851 in Healthy Adult Subjects
Influenza
Phase 12016-05-11
CompletedSafety, Tolerability, and Immunogenicity of VAL-506440 in Healthy Adult Subjects
Influenza
Phase 12015-12-01