Clinical Trials Directory

Trials / Sponsors / Melinta Therapeutics, Inc.

Melinta Therapeutics, Inc.

Industry · 32 registered clinical trials.

StatusTrialPhaseStarted
TerminatedA Study Comparing the Bioavailability of a Taste-masked Delafloxacin Powder for Oral Suspension With the Delaf
Healthy
Phase 12024-06-03
CompletedRelative Exposure and Safety Study of Kimyrsa in ABSSSI Patients
Acute Bacterial Skin and Skin Structure Infection
Phase 12019-07-16
WithdrawnA Study of Meropenem-Vaborbactam Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired and Ven
Hospital-Acquired Bacterial Pneumonia, Ventilator-Associated Bacterial Pneumonia, Hospital-Acquired Pneumonia
Phase 32018-08-01
CompletedEvaluate Safety and Pharmacokinetic To Assess Bronchopulmonary Disposition of Intravenous Delafloxacin in Heal
Pneumonia
Phase 12018-04-30
CompletedA Retrospective Observational Study to Evaluate the Utilization, Outcomes, and Adverse Events in Participants
Gram-Positive Bacterial Infections
2017-04-12
CompletedStudy to Compare Delafloxacin to Moxifloxacin for the Treatment of Adults With Community-acquired Bacterial Pn
Community Acquired Bacterial Pneumonia
Phase 32016-12-14
TerminatedSafety and Efficacy of Solithromycin in Adolescents and Children With Community-Acquired Bacterial Pneumonia
Community-acquired Bacterial Pneumonia
Phase 2 / Phase 32016-04-01
CompletedSafety and Efficacy of Solithromycin in the Treatment of Nonalcoholic Steatohepatitis Without Cirrhosis
Nonalcoholic Steatohepatitis
Phase 22015-12-01
CompletedStudy to Evaluate the Effect of Delafloxacin on the Pharmacokinetics of Midazolam in Healthy Subjects
VA Drug Interactions
Phase 12015-06-01
CompletedMultiple Oritavancin Doses on Safety, Tolerability, and Pharmacokinetics in Healthy Subjects
Healthy
Phase 12015-06-01
CompletedDrug-Drug Interaction Potential of Orbactiv (Oritavancin) Co-Administered With Warfarin in Healthy Subjects
Healthy
Phase 12015-04-01
CompletedOritavancin on the Results of Multiple Coagulation Tests in Healthy Volunteers
Healthy Volunteers
Phase 12015-01-01
CompletedPharmacokinetics and Safety of Solithromycin in Adolescents and Children
Bacterial Infection
Phase 12015-01-01
CompletedEfficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP
Urinary Tract Infection Complicated, Acute Pyelonephritis
Phase 32014-11-20
CompletedPharmacokinetics of Delafloxacin in Subjects With and Without Hepatic Impairment
Hepatic Impairment
Phase 12014-09-01
CompletedEfficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin i
Uncomplicated Urogenital Gonorrhea
Phase 32014-08-01
CompletedDelafloxacin vs Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infectio
Skin and Subcutaneous Tissue Bacterial Infections, Skin Structures and Soft Tissue Infections
Phase 32014-05-01
TerminatedComparison of Delafloxacin Versus Ceftriaxone for the Treatment of Uncomplicated Gonorrhea
Gonorrhea
Phase 32014-01-23
CompletedPharmacokinetics and Safety of Solithromycin Capsules in Adolescents
Bacterial Infections
Phase 12013-12-01
CompletedEfficacy and Safety Study of Intravenous to Oral Solithromycin (CEM-101) Compared to Intravenous to Oral Moxif
Community-acquired Bacterial Pneumonia
Phase 32013-11-01
CompletedDelafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infe
Skin and Subcutaneous Tissue Bacterial Infections
Phase 32013-04-01
CompletedOpen Label Study Evaluating the Effects of a Single Oritavancin Infusion on Cytochrome P450 in Healthy Volunte
Healthy
Phase 12013-01-01
CompletedA Study to Assess the Cardiac Safety of Oritavancin in Healthy Participants
Healthy
Phase 12012-12-27
CompletedEfficacy and Safety Study of Oral Solithromycin (CEM-101) Compared to Oral Moxifloxacin in Treatment of Patien
Community-acquired Bacterial Pneumonia
Phase 32012-12-01
CompletedSafety and Efficacy Study of Single-Dose Oral CEM-101 in Patients With Uncomplicated Urogenital Gonorrhea
Uncomplicated Urogenital Gonorrhea
Phase 22012-05-01
CompletedA Study to Assess Objective Endpoint Measurements of Response in Bacterial Skin Infections
Skin and Subcutaneous Tissue Bacterial Infections
Phase 22011-01-01
CompletedOritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure In
Wound Infection, Abscess, Systemic Inflammation
Phase 32010-12-01
CompletedOritavancin Versus IV Vancomycin for the Treatment of Participants With Acute Bacterial Skin and Skin Structur
Wound Infection, Abscess, Systemic Inflammation
Phase 32010-12-01
CompletedEfficacy and Safety Study of Oral CEM-101 Compared to Oral Levofloxacin in Treatment of Patients With Communit
Community-Acquired Bacterial Pneumonia
Phase 22010-08-01
CompletedSafety and Efficacy Study of a Fluoroquinolone to Treat Complicated Skin Infections
Skin Structure Infections, Bacterial Skin Diseases, Staphylococcal Skin Infections
Phase 22008-06-01
CompletedSafety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections
Infectious Skin Diseases, Bacterial Skin Diseases, Staphylococcal Skin Infections
Phase 22007-12-01
CompletedSafety and Efficacy Study of Oxazolidinone to Treat Pneumonia
Community-Acquired Pneumonia (CAP)
Phase 22007-10-01