Clinical Trials Directory

Trials / Completed

CompletedNCT02510599

Safety and Efficacy of Solithromycin in the Treatment of Nonalcoholic Steatohepatitis Without Cirrhosis

An Open Label, Proof of Principle Study to Evaluate the Efficacy and Safety of Solithromycin for the Treatment of Nonalcoholic Steatohepatitis Without Cirrhosis

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
10 (actual)
Sponsor
Melinta Therapeutics, Inc. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the effects of solithromycin on hepatic histology and biomarkers in patients with nonalcoholic steatohepatitis.

Detailed description

Patients will be administered solithromycin for 13 weeks with regular safety visits and liver biopsies at baseline and after treatment.

Conditions

Interventions

TypeNameDescription
DRUGsolithromycin

Timeline

Start date
2015-12-01
Primary completion
2017-01-27
Completion
2017-02-28
First posted
2015-07-29
Last updated
2017-03-21

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02510599. Inclusion in this directory is not an endorsement.

Safety and Efficacy of Solithromycin in the Treatment of Nonalcoholic Steatohepatitis Without Cirrhosis (NCT02510599) · Clinical Trials Directory