NCT06612255

A Study Comparing the Bioavailability of a Taste-masked Delafloxacin Powder for Oral Suspension With the Delafloxacin Tablet in Healthy Adults

A Phase 1, Single Part, Partially Randomised, Open-Label Study to Evaluate the Relative Bioavailability of a Taste-Masked Delafloxacin Powder for Oral Suspension With Oral Delafloxacin Tablet Reference in Healthy Subjects

• Status: Terminated
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Melinta Therapeutics, Inc. · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study will compare the bioavailability of a novel powder for oral suspension formulation of delafloxacin, intended for treatment of community acquired bacterial pneumonia, to that of the licensed delafloxacin oral tablet in healthy adults.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Delafloxacin	Delafloxacin tablet
DRUG	Delafloxacin Powder	Delafloxacin powder for oral suspension formulation

Timeline

• Start date: 2024-06-03
• Primary completion: 2024-09-11
• Completion: 2024-09-11
• First posted: 2024-09-25
• Last updated: 2025-09-26
• Results posted: 2025-09-26

Locations

1 site across 1 country: United Kingdom

Regulatory

• FDA-regulated drug study