Clinical Trials Directory

Trials / Sponsors / Centre Georges Francois Leclerc

Centre Georges Francois Leclerc

Academic / Other · 73 registered clinical trials16 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingA Study Evaluating the Contribution of Non-Coplanar Beam Arrangement in Reducing Toxicity in Radiotherapy for
Squamous Cell Carcinoma of the Oral Cavity and Oropharynx
N/A2026-04-01
Not Yet RecruitingPredicting Response to Anti-PD-1/PD-L1 Immunotherapy by Plasma Extracellular Vesicle Analysis
Non-Small Cell Lung Cancer, Melanoma (Skin Cancer)
2026-03-01
Not Yet RecruitingEmergence of Bacterial Resistance to Antibiotics in the Digestive Microbiota of Patients Treated With Anticanc
Cervical Cancers, Endometrial Cancer, Gynecological Cancers
N/A2025-09-01
Not Yet RecruitingEvaluation of the Effect of Adapted Physical Activity on the Modification of Lipid Metabolism During Chemother
Metastatic Colorectal Cancer (CRC), Volunteer Subjects
Phase 22025-06-01
RecruitingStudy of Cancer Patients' Preferences for Genetic Information Modalities Preceding Theranostic Exome Analysis.
All Types of Metastatic Solid Malignancy, 1st-line Treatment, Exome Analysis
N/A2024-09-19
RecruitingClinical Trial Evaluating the Safety and Efficacy of Chemoimmunotherapy Plus Short Course of Mek Inhibitor in
Non-Small Cell Lung Cancer
Phase 1 / Phase 22024-07-30
RecruitingUse of an Ultra-rapid BRCA1/2 Status Screening Test in Diagnostic and Theranostic Indication: Performance and
Breast Cancer
2024-06-12
RecruitingRandomized Study Versus Placebo for the Prevention of Neurotoxicity Induced by Weekly PACLITAXEL
Breast Cancer
Phase 22024-04-12
Not Yet RecruitingEvaluation of the Concordance Between Pre-therapy Dosimetry Performed From 68Ga-PSMA-11 Dynamic PET and Post-t
Patients With Metastatic Castration-resistant Prostate Cancer
N/A2024-01-31
RecruitingTrial Evaluating the Efficacy and the Safety of FOLFIRINOX3 Treatment in Patients With Unresectable Locally Ad
Metastatic Pancreatic Cancer
Phase 22024-01-24
Active Not RecruitingInfluence of Food Preferences on the Occurrence of Undernutrition in Treated Patients for Bronchopulmonary Car
Non-small Cell Bronchopulmonary Carcinoma at Stage IV and Benefiting From First-line Treatment According to Current French Recommendations
N/A2023-11-01
RecruitingImpact of Non-magnetic Screen Respiratory Self-guidance During MRI-guided Radiotherapy Sessions for Mobile Les
Patient With Radiotherapy (Linac MRI), Mobile Cancerous Lesion
N/A2023-10-16
UnknownStudy Evaluating the Safety and the Efficacy of Combination of Atezolizumab, Tiragolumab and and Stereotactic
Metastatic Non Small Cell Lung Cancer, Metastatic Bladder Cancer, Metastatic Renal Cell Carcinoma
Phase 12022-12-05
Active Not RecruitingFunctional Evaluation After Breast Reconstruction With a Minimally Invasive Latissimus Dorsi Flap Following Ra
Breast Cancer
N/A2022-11-25
Active Not RecruitingEvaluation of Efficacy of Trifluridine/Tipiracil Plus an Anti-IL-1α True Human Antibody Versus Trifluridine/Ti
Metastatic Colorectal Cancer
Phase 1 / Phase 22022-10-13
CompletedEvaluation and Modeling of the Effect of G-CSF on the Evolution of Polynuclear Neutrophils During Dense Dose E
Localized Breast Cancer
N/A2022-09-02
UnknownEvaluation of the Unconformity of the Hormonal Status of Metastatic Lesions During a First Relapse of Breast C
FES TEP in Detection of Estrogen Receptors
N/A2021-10-18
CompletedMechanisms of Anti COVID-19 Humoral and Cellular Immune Response After Vaccination in a Sample of Patients and
Cancer
N/A2021-06-02
UnknownHealth-Related Quality of Life Coupled With Therapeutic Information on Compliance to Endocrine Therapy in Brea
Breast Cancer
N/A2021-05-14
RecruitingFCH vs FDG PET/CT in Detection of Lesions in Patients With Multiple Myeloma (MIM)
Multiple Myeloma
N/A2020-12-15
UnknownModifications in Retinal Microvascularization With Targeted Anti-angiogenic Therapy in Colorectal Cancer
Colorectal Cancer
N/A2020-12-14
Active Not RecruitingEvaluation of the Efficacy and the Safety of a Stereotaxic Prostatic Radiotherapy Delivered With Linac MRI, in
Adenocarcinoma of the Prostate
N/A2020-10-01
CompletedIn Situ Immune Parameters and Their Prognostic Role on the Survival of Patients With Glioblastoma
Glioblastoma
2020-09-13
RecruitingExome Analysis (Complexe vs Simple) to Help the Therapeutic Decision for the Precision Medicine
Cancer
Phase 22020-08-25
UnknownImmuno Monitoring in Patient With Epithelial Ovarian Cancer Eligible to PARP Inhibitors
Ovarian Cancer
2020-07-07
RecruitingImmunomonitoring of Breast Cancer Patients During Systemic Treatment
Breast Cancer
N/A2020-05-26
CompletedStudy of the Specific Seroprevalence of SARS-CoV-2 in a Sample of Patients and Salaried Staff From a French An
Cancer
2020-05-12
Active Not RecruitingStudy Evaluating the Efficacy of a Double Immunotherapy Combined With Olaparib in Patients With Solid Cancers
Immunotherapy
Phase 22020-02-10
Active Not RecruitingAdaptative MR-Guided Stereotactic Body Radiotherapy of Liver Tumors
Radiotherapy
N/A2020-01-20
UnknownValue of Information of Secondary dAta in ONCOGEnetics
Cancer, Genetic Predisposition, Secondary Fundings
2019-12-09
RecruitingEXOME Analysis Position in the Strategy of Genetic Predisposition Factors Identification in Early-onset Cancer
Cancer, Genetic Predisposition
N/A2019-10-07
Active Not RecruitingEvaluation of the Accuracy of Percutaneous Biopsy by Vacuum-assisted Biopsy (VAB) to Assess Pathological Compl
Vacuum-assisted Biopsy
N/A2019-08-30
TerminatedEvaluation of the Impact of a Pharmaceutical Interview on the Adherence to Hormonotherapy in Women With Breast
Breast Cancer
N/A2019-06-25
UnknownAssessment of Health Related Quality of Life in Women Who Underwent Breast Reconstruction After Radical Surger
Breast Cancer
2019-05-04
CompletedStudy of Exosomes in Monitoring Patients With Sarcoma (EXOSARC)
Sarcoma
2018-11-19
Active Not RecruitingEvaluation of the Efficacy and the Safety of FOLFIRINOX3 Bevacizumab Treatment in Patients With Colorectal Can
Colorectal Cancer
Phase 1 / Phase 22018-11-07
CompletedValidation of a Genetic Signature to Predict the Development of Sarcomas
Genetic Signature in Development of Sarcomas
2018-06-19
TerminatedOptimizing the Management of Patients With Oral Therapy
Kidney Cancer, Breast Cancer
N/A2018-05-22
CompletedEvaluation of GEMCITEST in Patients With Pancreatic Cancer and Treated by Chemotherapy
Pancreatic Cancer
2018-01-30
RecruitingStudy Evaluating the Efficacy and the Tolerance of Pelvic-prostatic Hypo-fractionated Radiotherapy Followed by
To Evaluate the Rate of Digestive and Urinary Toxicity
N/A2018-01-24
CompletedEvaluation of the Safety and the Tolerability of Durvalumab Plus Tremelimumab Combined With FOLFOX in mCRC
Colorectal Cancer Metastatic
Phase 1 / Phase 22017-08-29
Active Not RecruitingStudy Evaluating the Efficacy of Radiotherapy With SIB-IMRT, Associated With Temozolomide in Glioblastomas
Glioblastoma, Adult
N/A2017-04-07
CompletedPemetrexed in Maintenance in Patients With Impaired Renal Function, 2 Dose Calculation Strategies
Non-small Cell Lung Cancer
Phase 42017-04-06
TerminatedMultimetabolic 18F-Fluorodeoxyglucose (FDG) and 18F-Fluorocholine (FCH) Positron Emission Tomography (PET) as
Carcinoma, Hepatocellular
N/A2017-03-27
CompletedCharacteristics of the Intestinal Microbiota in Patients With Cancer
Oncology
N/A2017-02-06
CompletedObservational Study to Assess Adherence Oral Anticancer Therapies
Adherence, Patient
2016-12-23
CompletedPreoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers
Advanced Rectal Cancers
N/A2016-12-22
CompletedTriple Negative Breast Cancer: Identification Pilot Study of Predictive Transcriptome Profiles of Early Tumor
Breast Neoplasms
N/A2016-11-08
CompletedA Positron Emission Tomography (PET) Imaging Agent [18F]-ODS2004436 as a Marker of EGFR Mutation in Subjects W
Carcinoma, Non-Small-Cell Lung
N/A2016-09-27
CompletedWhat Benefit of a Full Analysis of Exome? Routine Care Study in Patients With Solid Tumors
Carcinoma
2016-05-15
CompletedPilot Study With the Aim to Quantify a Stress Protein in the Blood and in the Urine for the Monitoring and Ear
Cancer
N/A2015-12-15
CompletedEvaluation and Modeling of the G-CSF Effect on the Evolution of Neutrophils During Chemotherapy Based on Eribu
Breast Cancer
N/A2015-12-03
CompletedOsteopathy and Prevention of Gastrointestinal Side Effects in Women Treated for Breast Cancer
Breast Cancer
N/A2015-11-05
Active Not RecruitingStudy Evaluating the Utility of 18F-FDG PET in Assessing Early Response to Neoadjuvant Chemotherapy in Patient
FDG PET
N/A2015-03-25
TerminatedEvaluation of the Dose Received by the Prostate With in Vivo Dosimetry in Patients Treated With Daily IGRT Ass
Prostate Cancer
N/A2014-12-22
CompletedNGS Genome Analysis in Personalisation of Lung Cancer Treatment
Lung Cancer
N/A2014-10-24
CompletedStudy Evaluating the Influence of LV5FU2 Bevacizumab Plus Anakinra Association on Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Phase 22014-10-10
CompletedStudy of Microcirculatory Effects of Bevacizumab in Patients Treated for Metastatic Colon Cancer or Glioblasto
Metastatic Colorectal Cancer, Glioblastoma, Bevacizumab
N/A2013-05-01
CompletedBrachytherapy for Recurrent Prostate Cancer
Recurrent Prostate Cancer, Brachytherapy Remedial
Phase 22013-03-26
UnknownMetastatic Colorectal Cancer Database
Metastatic Colorectal Cancer
2012-11-26
TerminatedSafety Study of Pelvic and Prostatic SIB-IMRT With Long-term Androgen Deprivation for High Risk Localized Pros
Prostate Cancer
Phase 22012-10-01
UnknownRelevance of T Lymphocytes Tumor Infiltrates CD8 and Foxp3 as Immune Prognostic Biomarker in Breast Cancer Tre
Breast Cancer
N/A2012-05-01
CompletedPredictive Study of Radiation Induced Sarcoma
Radiation Induced Sarcoma
N/A2011-12-01
CompletedRadiochemotherapy With and Without Dose Escalation in Patients Presenting Locally Advanced or Inoperable Carci
Esophageal Cancer
Phase 2 / Phase 32011-05-06
TerminatedFeasibility of the Research for Mutation of K-ras and EGFR in CTCs From Metastatic Non Small Cells Bronchial C
Non-small Cell Lung Cancer Metastatic
EARLY_Phase 12011-03-09
CompletedHepatic Arterial Chemotherapy With Raltitrexed and Oxaliplatin Versus Standard Chemotherapy in Unresectable Li
Colorectal Cancer, Liver Metastases
Phase 22010-12-15
UnknownNeoadjuvant Database
Neoadjuvant Treatment in Breast Cancer
2009-09-09
UnknownQuality-Of-Life Assessment in Patients With Head and Neck Cancer Treated With Radiation Therapy
Head and Neck Cancer
2009-09-01
CompletedDose Escalation Radiotherapy With Modulation of Intensity and Integrated Boost (SIB-IMRT) in the Treatment of
Glioblastoma
Phase 12009-09-01
CompletedEvaluation of the Irinotecan/Bevacizumab Association for Naive Unresectable Glioblastoma
Naive Unresectable Glioblastoma
Phase 22009-01-01
CompletedLapatinib in Combination With Docetaxel in Patients With HER-2 Positive Advanced or Metastatic Breast Cancer
Metastatic Breast Cancer
Phase 1 / Phase 22008-11-01
CompletedSpectro-IRM and Evaluation Response to Prostatic Radiotherapy
Prostate Cancer
N/A2008-02-01
UnknownThyroid Cancer Database
Patients With a Thyroid Tumor Who Received Radioactive Iodine Treatment
2000-01-01