Trials / Completed
CompletedNCT03200249
Preoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers
Preoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers: Phase 2 Study (RADICAL)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 15 (actual)
- Sponsor
- Centre Georges Francois Leclerc · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
Hypothesis : Therapeutic intensification by increasing the dose delivered to the tumor by RCMI (conformational radiotherapy by intensity modulation) in order to reduce local relapse, often associated with poor prognosis Primary objective: evaluate the rate of tumor sterilization and the toxicities of RTCT with concomitant boost in intensity modulation in patients with rectal cancer CT3-T4 and / or cN1-2.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | Preoperative chemo-radiation with IG-IMRT dose escalation |
Timeline
- Start date
- 2016-12-22
- Primary completion
- 2016-12-22
- Completion
- 2020-01-07
- First posted
- 2017-06-27
- Last updated
- 2020-06-24
Locations
2 sites across 1 country: France
Source: ClinicalTrials.gov record NCT03200249. Inclusion in this directory is not an endorsement.