NCT03195972

Observational Study to Assess Adherence Oral Anticancer Therapies

Observational Study to Assess Adherence of Oral Anticancer Therapies

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 200 (actual)
• Sponsor: Centre Georges Francois Leclerc · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Oral anticancer treatments are increasingly numerous. They represent an additional alternative in the therapeutic arsenal of the clinician, and appear to satisfy patients who prefer this route of administration over intravenous treatment. The objective of oral therapies is twofold: to remove the constraints and risks associated with infusions and to allow the patient to follow his treatment at home. However, they have significant adverse effects that may affect patients, who are sometimes at a disadvantage compared to how they are treated, and potentially lead to non-compliance with the consequences. This study will identify the factors associated with non-adherence and determine the impact of this non-adherence in terms of treatment efficacy and tolerance. The aim of this routine care study is to evaluate the adherence to oral anticancer therapies during 3 months.

Detailed description

Primary objective \- To evaluate adherence to oral anti-cancer therapies at 3 months Secondary objectives * To evaluate the adherence to 3 months according to the age of the patients (less than 75 years versus 75 years and more) * Evaluate compliance at 1 and 2 months * Evaluate toxicity at 1, 2 and 3 months according to compliance according to criteria CTCAE 4.03. * Evaluate response to treatment at 3 months based on adherence * Evaluate the factors associated with adherence and describe the reasons for non-adherence.

Conditions

• Adherence, Patient

Interventions

Type	Name	Description
OTHER	Drug diary filling	patient will fill every day a drug diary

Timeline

• Start date: 2016-12-23
• Primary completion: 2016-12-23
• Completion: 2018-09-04
• First posted: 2017-06-22
• Last updated: 2019-11-05

Locations

1 site across 1 country: France