| Not Yet Recruiting | Prospective Clinical Evaluation of the Safety and Performance of the Aesthetic Medical Device MEC REGENERATE® NCT07413445 | 303 Pharma s.r.l. | N/A |
| Recruiting | Post-market Clinical Follow-up (PMCF) Study of Safety and Performance of 502-01 AnGelHA 2 NCT07495865 | Glyance | — |
| Not Yet Recruiting | Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improvi NCT07324759 | NovoBliss Research Pvt Ltd | N/A |
| Active Not Recruiting | A Clinical Study to Test the Safety and Effectiveness of Pinorox® for Improving Visible Signs of Facial Aging NCT07111156 | NovoBliss Research Pvt Ltd | N/A |
| Not Yet Recruiting | PER-SAF_PDOS (Performance and Safety of Polydioxanone Suture) NCT07068061 | 21 Century Medical Co., Ltd. | N/A |
| Completed | Evaluation of the Efficacy of a Cosmetic Light Mask NCT07054710 | Therabody, Inc. | N/A |
| Not Yet Recruiting | Quantified Evaluation of Whole Face 8-points Supra-periosteum High Molecular Weight Hyaluronic Acid Injection NCT06871592 | Chang Chang Cheng | — |
| Completed | The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen and MSM on Skin NCT06755892 | VIST - Faculty of Applied Sciences | N/A |
| Recruiting | Safety and Efficacy Evaluation of High Intensity Focused Ultrasound Device in Eyebrow Lifting NCT06724510 | CLASSYS Inc. | N/A |
| Completed | Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles NCT06657365 | CLASSYS Inc. | N/A |
| Completed | Single-Blind, Investigational Device Exemption Paired-Design, Non-Inferiority Trial With Confirmation for the NCT07467811 | TENTECH INC. | N/A |
| Completed | Post Market Non-Interventional Study of Safety and Performance of RefillHA Volume NCT07329608 | Glyance | — |
| Completed | Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions NCT05847530 | Cynosure, Inc. | N/A |
| Completed | The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin NCT05730517 | VIST - Faculty of Applied Sciences | N/A |
| Completed | A Clinical Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment For Facial Rejuvenatio NCT06629792 | Revision Skincare | N/A |
| Completed | The Effect of 12-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin NCT04988412 | VIST - Faculty of Applied Sciences | N/A |
| Completed | Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device NCT05254210 | Cynosure, Inc. | N/A |
| Completed | The Effect of Topical Almond Oil vs. Topical Retinol on The Appearance of Facial Wrinkles NCT05011461 | University of California, Davis | N/A |
| Completed | Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment NCT05089851 | Revision Skincare | N/A |
| Completed | A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines NCT04545970 | Revision Skincare | N/A |
| Completed | Efficacy and Tolerability of SkinPen on Male and Female Subjects' Wrinkles of the Neck NCT03803059 | Bellus Medical, LLC | N/A |
| Completed | The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin P NCT03811756 | VIST - Faculty of Applied Sciences | N/A |
| Completed | Pilot Study of Triphala and Rubia Cordifolia on Gut Microbiome and Skin NCT03477825 | University of California, Davis | N/A |
| Completed | Astaxanthin (2 mg) + Lycopene (1.8 mg) + D-Alpha-Tocopherol (10 IU) For The Treatment Of Skin Aging NCT03460860 | United Laboratories | N/A |
| Completed | Study of a Novel Microlens Array Device for Skin Rejuvenation NCT02888626 | Cutera Inc. | N/A |
| Completed | Comparison of Dysport Reconstitution at 1.5 mL and 2.5 mL for the Treatment of Moderate to Severe Glabellar Li NCT02718118 | Galderma R&D | Phase 4 |
| Completed | Emervel for the Correction of Lower Face Wrinkles & Folds NCT02718040 | Galderma R&D | Phase 4 |
| Completed | Non-comparative Evaluation of Facial Expressions Following Lower Face Correction Using Emervel Classic and Eme NCT02672644 | Galderma R&D | Phase 4 |
| Completed | Silk'n HST Device Usability and Self Selection Study NCT02919007 | Home Skinovations Ltd. | N/A |
| Completed | Silk'n HST for Wrinkle Reduction - Clinical Study Protocol NCT02913547 | Home Skinovations Ltd. | N/A |
| Completed | Sculptra Aesthetic Post-Approval Study NCT02425943 | Galderma R&D | Phase 4 |
| Completed | Influence of of Cream With the Silver Fir Wood Extract (Belinal) on Skin NCT02603029 | VIST - Faculty of Applied Sciences | N/A |
| Completed | Clinical Trial to Evaluate Safety and Efficacy of Ultherapy™ System for Lifting Skin on the Neck NCT02368925 | Seoul National University Hospital | N/A |
| Completed | Safety and Efficacy Evaluation of Ultherapy™ System in Aging Hand NCT02364440 | Seoul National University Hospital | N/A |
| Completed | Effects of Application LED Therapy and Laser Therapy in Facial Rejuvenation NCT02513680 | Federal University of Health Science of Porto Alegre | N/A |
| Completed | Assessment of the Impact of a Coenzyme Q10 Supplementation on the Skin NCT02604641 | VIST - Faculty of Applied Sciences | N/A |
| Completed | A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Classic Plus Versus YVOIRE Classic in Nasolabia NCT02340091 | LG Life Sciences | N/A |
| Completed | Injectable Filler for Facial Soft Tissue Augmentation NCT02218788 | Panaxia Ltd | — |
| Active Not Recruiting | A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles NCT02019004 | Northwestern University | EARLY_Phase 1 |
| Completed | A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Volume Plus Versus YVOIRE Volume in Nasolabial NCT02340078 | LG Life Sciences | N/A |
| Completed | Prospective Study Evaluating the Treatment of Hyperdynamic Forehead Wrinkles NCT01984619 | Pacira Pharmaceuticals, Inc | — |
| Completed | Evaluation of the Safety and Efficacy of the Pico Laser With a Specialized Lens Array for the Treatment of Wri NCT02091089 | Cynosure, Inc. | N/A |
| Completed | Evaluating the Safety and Efficacy of the Pico Laser With a Specialized Lens Array for the Treatment of Wrinkl NCT02091102 | Cynosure, Inc. | N/A |
| Unknown | Epidermal Delivery of Ani-Aging Ingredients NCT01847066 | Alma Lasers Inc. | N/A |
| Completed | TriActive+ Radiofrequency (RF) for Non-Invasive Treatment of Wrinkles and Rhytides NCT01859611 | El. En. SpA | N/A |
| Terminated | Collagen Injections for the Treatment of Acne Scars and Wrinkles NCT01704209 | Northwestern University | Phase 1 |
| Completed | Safety Study of Antria Cell Preparation Process to Enhance Facial Fat Grafting With Adipose Derived Stem Cells NCT01828723 | Antria | Phase 1 |
| Completed | Clinical Evaluation of M22 ResurFX 1565nm Module NCT01796626 | Lumenis Be Ltd. | N/A |
| Completed | Clinical Trial on a Topical "Antiage" Face Gel NCT01948531 | Derming SRL | Phase 4 |
| Completed | Feasibility Study: Evaluation of Ulthera Versus Thermage for Treating the Face and Neck NCT01713985 | Ulthera, Inc | N/A |
| Completed | Fractional Ablative Radiofrequency for the Treatment of Acne Scars and Wrinkles NCT01645345 | Alma Lasers Inc. | N/A |
| Completed | Safety and Efficacy of the Luxe Device to Treat Facial Wrinkles and Rosacea NCT01618864 | Syneron Medical | N/A |
| Active Not Recruiting | Fractional Laser vs. Ultrasound for Periorbital Wrinkles NCT01529983 | Northwestern University | EARLY_Phase 1 |
| Completed | A Retrospective Study to Evaluate the Effectiveness of the Ulthera System NCT01519934 | Ulthera, Inc | — |
| Completed | TriActive+ Radiofrequency (RF) for Non-invasive Treatment of Wrinkles & Rhytides NCT01460927 | Deka Medical, Inc. | N/A |
| Completed | Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A NCT01586819 | Loyola University | Phase 3 |
| Completed | Efficacy and Safety of a New Botulinum Toxin Type A for Treatment of Facial Expression Lines NCT01180348 | Azidus Brasil | Phase 3 |
| Terminated | Evaluation of the Ulthera® System for Treatment of the Face and Neck NCT01713907 | Ulthera, Inc | N/A |
| Completed | Radial Diffusion of the Botulinum Toxin Type A (Botox®): Electromyographic Evaluation of the Frontal Muscle NCT01297634 | Ivo Pitanguy Institute | Phase 4 |
| Completed | Non-inferiority of Belotero® Basic Versus Juvéderm® Ultra 3 NCT01305187 | Merz Pharmaceuticals GmbH | Phase 4 |
| Completed | Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds NCT01269801 | AboutSkin Dermatology and DermSurgery, PC | Phase 4 |
| Completed | Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles NCT01283464 | Johns Hopkins University | Phase 2 |
| Unknown | A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0. NCT01267149 | Goldman, Butterwick, Fitzpatrick and Groff | — |
| Withdrawn | Wrinkle Injection With Autologous Platelet Rich Plasma Study NCT01078493 | Novena Medical Center | Phase 1 |
| Completed | Outcomes and Patient Experience After Soft Tissue Dermal Filler Injections NCT01034956 | The New York Eye & Ear Infirmary | — |
| Completed | Comparison of Two Botulinum Toxins Type A on Forehead Wrinkles NCT01014871 | Galderma R&D | Phase 2 |
| Completed | Safety and Efficacy of a Metallic Cannula Versus A Standard Needle for Soft Tissue Augmentation of the Nasolab NCT01066026 | Hexsel Dermatology Clinic | Phase 2 |
| Completed | Safety Study of Cosmetic Tissue Augmentation in People of Color NCT01147172 | Anika Therapeutics, Inc. | N/A |
| Completed | Argireline in Treatment of Periorbital Wrinkles NCT01381484 | Mahidol University | Phase 3 |