NCT01078493

Wrinkle Injection With Autologous Platelet Rich Plasma Study

Phase 1 Study of Intradermal Injection of Autologous Platelet Rich Plasma for Facial Wrinkles

• Status: Withdrawn
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Novena Medical Center · Network
• Sex: All
• Age: 21 Years
• Healthy volunteers: Accepted

Summary

Wrinkles result from imperfect repair of the dermal layer resulting in loss of collagen commonly due to ageing, smoking and sun exposure. Platelet rich plasma (PRP) contains a host of growth factors, which have been used in other clinical trials for various medical conditions such as tendonitis, and also in surgery such as the surgical repair of facial defects. Results from these clinical trials suggest that PRP helps in collagen formation and organisation to promote healing of tissues. This study attempts to document the clinical effects of intradermal injection of PRP on wrinkles.

Detailed description

10 selected participants will have 10 ml of blood removed for platelet extraction with MyCells®. The resulting Platelet rich plasma will be injected intradermally into the facial wrinkles.

Conditions

• Wrinkles

Interventions

Type	Name	Description
DEVICE	MyCells® (injection of platelet rich plasma)	PRP contains at least 1,000,000 platelets per mm3 or 2-6 times the native concentration of whole blood at a pH of 6.5 to 6.7

Timeline

• Start date: 2010-02-01
• Primary completion: 2012-02-01
• Completion: 2012-05-01
• First posted: 2010-03-02
• Last updated: 2016-09-26

Locations

1 site across 1 country: Singapore