| Not Yet Recruiting | Low-dose Colchicine for Thromboprophylaxis After Transcatheter Aortic Valve Replacement NCT07411768 | China National Center for Cardiovascular Diseases | N/A |
| Not Yet Recruiting | TAVR for Aortic Regurgitation Under TEE Guidance NCT07453849 | Chinese Academy of Medical Sciences, Fuwai Hospital | N/A |
| Not Yet Recruiting | Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients NCT07329660 | Air Force Military Medical University, China | N/A |
| Not Yet Recruiting | Transcatheter Mitral and Tricuspid Interventions: a Cardiac Magnetic Resonance Study NCT07370467 | Centro Cardiologico Monzino | — |
| Recruiting | Comparison of Single vs. Dual Perclose Devices for Large-Bore Access Closure in TAVR NCT06871774 | Wake Forest University Health Sciences | N/A |
| Recruiting | Clinical Feasibility and Evaluation Study of POINT-GUARD Embolic Protection Device During TAVR (GUARDIAN) NCT06962371 | Transverse Medical, Inc. | N/A |
| Recruiting | Coronary Artery Disease Assessment Strategies in TAVI Patients NCT06559332 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | This Study Will Evaluate the Safety and Potential Complications of Dual ProGlide vs Single ProGlide and Angios NCT06983938 | Baylor Research Institute | N/A |
| Recruiting | Short Versus Long Antiplatelet Therapy After TAVI NCT06518317 | University Hospital, Caen | Phase 3 |
| Recruiting | TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics NCT06896227 | Heinrich-Heine University, Duesseldorf | N/A |
| Recruiting | Valve Performance of the SAPIEN 3 Ultra RESILIA Valve: A Prospective Registry With Central Echocardiography An NCT06420830 | Institut universitaire de cardiologie et de pneumologie de Québec, University Laval | — |
| Completed | Feasibility of Valve-in-Root Transcatheter Aortic Valve Implantation in 363 Patients After Aortic Root Replace NCT06697249 | Alicja Zientara | — |
| Recruiting | CT TAVR Abdomen Study NCT05758701 | University of Maryland, Baltimore | Phase 4 |
| Enrolling By Invitation | Feasibility, Safety, and Effectiveness of the ACURATE neo2 Transcatheter Heart Valve for Severe Bicuspid Aorti NCT06212050 | National University of Ireland, Galway, Ireland | — |
| Recruiting | Ischemic And Bleeding Risk Assessment After TAVR NCT06000943 | Niguarda Hospital | — |
| Unknown | Antithrombotic Strategy Based on Clinical Events and 4D-CT for Patients After TAVR NCT05375474 | China National Center for Cardiovascular Diseases | Phase 4 |
| Completed | Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Repl NCT05881291 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 4 |
| Terminated | Intra-procedural ECG Changes During TAVR NCT05791344 | Cara Medical Ltd | — |
| Unknown | The JUMPSTART Program: Encouraging Early Mobilization and Optimizing Recovery of TAVR Patients' Post-hospital NCT06040398 | Hamilton Health Sciences Corporation | — |
| Recruiting | COronary Re-engageMent aFter randOm NavitoR alignmenT (COMFORT STUDY) NCT05779787 | Niguarda Hospital | — |
| Withdrawn | Efficacy of Angiotensin Receptor Blocker Following aortIc Valve Intervention for Aortic STenOsis: a Randomized NCT03315832 | University Hospital, Limoges | Phase 2 / Phase 3 |
| Completed | Cara CDRS (Conduction Disturbance Risk Score) 1.0 NCT05657912 | Cara Medical Ltd | — |
| Unknown | Prognostic Factors in NOP-LBBB After TAVI NCT05654792 | Central Hospital, Nancy, France | — |
| Completed | Aortic Stenosis With COmplex PCI (ASCOP) Features Retrospective Registry on Contemporary Management and Outcom NCT05750927 | Niguarda Hospital | — |
| Unknown | TAVR in Adults With Pure Severe Aortic Regurgitation NCT05737264 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | — |
| Terminated | Cara CDRM (Conduction Disturbance Risk Monitor) 2.0 NCT05465655 | Cara Medical Ltd | N/A |
| Unknown | Ultrasound-guided Femoral Puncture to Reduce Access- Related Complications After TAVR: (ACCESS-TAVR SIRIO) NCT05637983 | Fondazione Toscana Gabriele Monasterio | N/A |
| Completed | The Sentinel Registry NCT05217888 | Duk-Woo Park, MD | — |
| Unknown | Coronary Access After Supra-Annular THV Implantation NCT05075590 | University of British Columbia | N/A |
| Completed | The SAVVY Guidewire in Transcatheter Aortic Valve Replacement Procedures NCT05082337 | Institut universitaire de cardiologie et de pneumologie de Québec, University Laval | N/A |
| Completed | Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement NCT04870424 | Insel Gruppe AG, University Hospital Bern | Phase 3 |
| Unknown | LUS in Aortic Stenosis Patients Undergoing TAVR NCT05024942 | Catholic University of the Sacred Heart | — |
| Completed | Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System NCT04982406 | Beth Israel Deaconess Medical Center | — |
| Enrolling By Invitation | Safety and Efficacy of SinocrownTM Transcatheter Aortic Valve Replacement System NCT05202977 | Lepu Medical Technology (Beijing) Co., Ltd. | N/A |
| Unknown | Assessment of Clinical Onset of IV Heparin in Interventional Cardiology and Cardiac Surgery NCT04785885 | Rhode Island Hospital | — |
| Unknown | Neuropsychological and Neuroimaging Evaluation of the Cognitive Impairment in Aortic Valve Replacement (ARTiCO NCT05235529 | Germans Trias i Pujol Hospital | — |
| Completed | The CAPTIS® Study - Embolic Protection in TAVR NCT04659538 | Filterlex Medical Ltd. | N/A |
| Withdrawn | GPx Activity in Subjects With Aortic Stenosis Undergoing TAVR NCT04268160 | University of Florida | — |
| Unknown | ADAPT Transcatheter Aortic Valve Intervention (TAVI & Chronic Total Occlusion Percutaneous Coronary Interventi NCT05259241 | Erasmus Medical Center | N/A |
| Completed | Observational Study on the Application of High-Flow Therapy After Percutaneous Transfemoral Aortic Valve Repla NCT04489914 | Drägerwerk AG & Co. KGaA | — |
| Unknown | Risk Stratification Post TAVI Using TEG NCT03649594 | Torben Pottgiesser | — |
| Unknown | The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergo NCT04573049 | China National Center for Cardiovascular Diseases | Phase 4 |
| Recruiting | SMART Watch Facilitated Early Discharge in Patients Undergoing Transcatheter Aortic Valve Replacement NCT04454177 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Unknown | TAVI in Intermediate Risk Septuagenarians With Risk Factors Not Captured by the Traditional Surgical Risk Scor NCT04517955 | University of Athens | — |
| Unknown | Physiological Reconditioning Program Administered Remotely in Patients Undergoing Transcatheter Aortic Valve R NCT03801460 | Unity Health Toronto | N/A |
| Recruiting | Prospective Validation of a Pre-Specified Algorithm for the Management of Conduction Disturbances Following TA NCT04139616 | Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec | — |
| Completed | Monitored Anesthesia Care vs. General Anesthesia for Transcatheter Aortic Valve Replacement NCT04107038 | Medical University of South Carolina | N/A |
| Active Not Recruiting | Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI NCT04281771 | Radboud University Medical Center | N/A |
| Unknown | The PERFORM-TAVR Trial NCT03522454 | Jewish General Hospital | N/A |
| Completed | Cognitive Outcome After Surgical and Transcatheter Aortic Valve Replacement NCT04535076 | Heart and Brain Research Group, Germany | N/A |
| Completed | Comparison of Procedural Sedation With Propofol and Dexmedetomidine During Transcatheter Aortic Valve Implanta NCT03747432 | University Medical Centre Ljubljana | Phase 4 |
| Completed | Anticoagulation Alone Versus Anticoagulation and Aspirin Following Transcatheter Aortic Valve Interventions (1 NCT02735902 | Centre Hospitalier Universitaire de Nīmes | Phase 4 |
| Unknown | Dual AntiPlatelet Therapies for Prevention of Periinterventional Embolic Events in TAVI NCT03001960 | Charite University, Berlin, Germany | Phase 3 |
| Completed | Evaluation of Cerebral Thrombembolism After TAVR NCT02758964 | Charite University, Berlin, Germany | — |
| Unknown | Biological Collection and Registry of Patients Who Will Have a TAVR (Transcatheter Aortic Valve Replacement) I NCT02812953 | Action, France | — |
| Unknown | HV Electrophysiology Study In Transcatheter Aortic Valve Implantation Patients NCT02659137 | Maastricht University Medical Center | — |
| Completed | Platelet Reactivity After TAVI: A Multicenter Pilot Study NCT02224066 | Hospital de Meixoeiro | Phase 4 |
| Terminated | Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Tra NCT02556203 | Bayer | Phase 3 |
| Recruiting | EffecTAVI Registry NCT05235555 | Federico II University | — |
| Completed | Sentinel(TM) Post-Market Registry NCT02255851 | Claret Medical | — |
| Completed | Exercise Training After Transcatheter Aortic Valve Implantation NCT01935297 | Technical University of Munich | N/A |
| Completed | Application of Emergent Peripheral Mechanical Circulatory Support in Transcatheter Aortic Valve Replacement fo NCT04464356 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Completed | REPRISE II: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus™ Va NCT01627691 | Boston Scientific Corporation | N/A |
| Completed | Open-label, Randomized Trial in Participants Undergoing TAVR to Determine Safety & Efficacy of Bivalirudin vs NCT01651780 | The Medicines Company | Phase 3 |
| Unknown | The Italian Society of Invasive Cardiology Registry on Percutaneous Aortic Valve NCT02713932 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | — |
| Completed | Post-TAVI Coronary Access Study NCT04649190 | Sheba Medical Center | — |