| Not Yet Recruiting | Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety NCT06236542 | Johns Hopkins University | N/A |
| Not Yet Recruiting | Invasive Home Ventilation in Denmark NCT07467187 | Rigshospitalet, Denmark | — |
| Not Yet Recruiting | Impact of Information and Participation on Decision Time for Tracheostomy or PEG in ICU Families NCT07435896 | Elazıg Fethi Sekin Sehir Hastanesi | — |
| Enrolling By Invitation | Standardized Tracheostomy Decannulation Protocol for Patients With Prolonged Disorders of Consciousness NCT07183670 | Hongying Jiang, MD | — |
| Not Yet Recruiting | Cough Flow as a Criterion Decannulation Threshold in Prolonged Tracheostomy Patients NCT07317791 | Hongying Jiang, MD | N/A |
| Not Yet Recruiting | The Effects of Listening to Fairy Tales, Listening to Fairy Tales in Their Mothers' Voices, and Watching Carto NCT07210346 | Ataturk University | N/A |
| Recruiting | SV With TTPEE Measurement Predicts Upper Airway Patency in Prolonged Tracheostomy Patients NCT07107243 | Capital Medical University | N/A |
| Completed | Comparison of Ventilatory Effects of Ultrasound-Guided Versus Bronchoscopy-Guided Percutaneous Dilatational Tr NCT07376525 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | — |
| Completed | Tracheostomy Practices in Adult Intensive Care Units: A Multicentre Study in Izmir NCT07404592 | Izmir City Hospital | — |
| Recruiting | "Airway Complications in Pediatric Patients With Tracheostomies: To What Extent Can Symptoms Identified by Car NCT07121517 | Karolinska Institutet | — |
| Not Yet Recruiting | Objective Evaluation of Cough Effort in Tracheotomized Patients (LOST Study) NCT07061561 | Centre Hospitalier de Saint-Denis | N/A |
| Completed | Hyperoxia vs Normoxia During Cardiopulmonary Bypass NCT07510672 | University of Padova | N/A |
| Recruiting | Feeding Difficulties and Quality of Life in Children With Tracheal Cannula NCT06893458 | Karolinska Institutet | — |
| Not Yet Recruiting | Comparison of Physiological Effects of Two Types of High-Flow Oxygen Therapy in Tracheostomized Patients NCT06816745 | Jian-Xin Zhou | N/A |
| Enrolling By Invitation | Use of TrachPhone in Tracheostomized Patients NCT06487104 | Atos Medical AB | N/A |
| Recruiting | Digital Health Pathway for Children With Medical Complexity Requiring Tracheostomy NCT06375369 | University of Alberta | N/A |
| Active Not Recruiting | The Effect of Percutaneous Dilatational Tracheostomy on Intracranial Pressure NCT06779877 | Akdeniz University | — |
| Recruiting | Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and T NCT06525818 | University of Chicago | N/A |
| Enrolling By Invitation | No DIET Trial: Dogmatic Interruption of Enteral nuTrition NCT06431048 | Jeffrey Coughenour | N/A |
| Enrolling By Invitation | Boosting Resources for Tracheostomy Care at Home NCT06283953 | Massachusetts General Hospital | N/A |
| Recruiting | Investigation of a 3 oz Water Protocol on Patients With Tracheostomies NCT06120790 | Icahn School of Medicine at Mount Sinai | — |
| Completed | Carbon Dioxide Investigation NCT06715410 | GE Healthcare | N/A |
| Completed | Personalized Decision-Aid to Guide Tracheostomy and Prolonged Mechanical Ventilation Decision-Making NCT07223918 | Denver Health and Hospital Authority | — |
| Unknown | Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients. NCT06201130 | Northwell Health | — |
| Recruiting | Outcomes After Tracheal Cannula Removal NCT06047665 | Katharina Winiker | — |
| Withdrawn | An Investigator-initiated Study to Evaluate Safety and Efficacy of ARINA-1 in People With a Tracheostomy NCT05658029 | Matthew Bruehl | Phase 1 |
| Completed | A Speech Recognition Application as a Communication Aid for Acute and Critical Care Patients With Tracheostomi NCT06027866 | Queen's University, Belfast | — |
| Completed | Continuous Enteral Feeding Until Tracheostomy and Aspiration Risk NCT07508293 | Bursa Yuksek Ihtisas Training and Research Hospital | — |
| Unknown | Lung Ultrasound Score After ENT Cancer Surgery NCT05482841 | Centre Leon Berard | — |
| Recruiting | Speaking Valve Influence on Breathing, Swallowing and Vocal Functions in Patients With Tracheostomy. NCT05482022 | Loewenstein Hospital | N/A |
| Completed | Safe and Effective Above Cuff Tracheostomy Ventilation NCT04647786 | Manchester University NHS Foundation Trust | N/A |
| Completed | Caregivers Tracheal Aspiration Training NCT05434442 | Uludag University | N/A |
| Completed | Percutaneous Tracheostomy NCT05343442 | Alexandria University | Phase 4 |
| Completed | Caregiver Experiences With Tracheostomy NCT05739578 | Uludag University | — |
| Unknown | Concordance of Methods to Select Tracheostomy Tube Size for Adults in Intensive Care NCT05047432 | University College, London | — |
| Completed | Does Endurance Improve With the Use of Passy-Muir Valve for Patients With Tracheostomy? NCT04941456 | Gaylord Hospital, Inc | N/A |
| Unknown | Effect of Body Tilting on Diaphragm Excursion and Thickness in the Stroke Patients With Tracheotomy by Ultraso NCT05041894 | Shenzhen Second People's Hospital | — |
| Unknown | Comparison of Effectiveness of Different Airway Management Methods During Percutaneous Tracheostomy NCT04872881 | Bozyaka Training and Research Hospital | Phase 4 |
| Completed | Determinants of Successful Decannulation in Difficult-to-wean Patients NCT04841889 | Hopital Forcilles | N/A |
| Recruiting | Primary vs Secondary Closure of Tracheo-cutaneous Fistulas NCT04647968 | Université de Sherbrooke | N/A |
| Completed | Quality of Life in Ventilator-dependant Neuromuscular Patients NCT04652401 | Centre d'Investigation Clinique et Technologique 805 | — |
| Terminated | The Application and Analysis of Diaphragm Electrical Impulse in Adult Patients With Spontaneous Breathing Tria NCT05241002 | Fu Jen Catholic University | — |
| Completed | Timing of Tracheostomy in COVID-19 - Impact on Mortality NCT05175859 | Goethe University | — |
| Completed | Percutaneous Tracheostomy With COVID-19 NCT04447638 | Çanakkale Onsekiz Mart University | — |
| Unknown | Mortality in Patients With Severe COVID-19 Pneumonia Who Underwent Tracheostomy NCT04642703 | University of Chile | — |
| Completed | Consequence of Open Versus Closed Tracheostomy Immediately After Decannulation NCT06138093 | Aarhus University Hospital | N/A |
| Completed | Early SARS-CoV-2 Tracheostomy NCT05520957 | Cantonal Hospital Zenica | — |
| Completed | Efficacy and Safety of the DYNAtraq Device to Prevent Complications in Tracheostomy in Mechanically Ventilated NCT04668742 | Fundación Cardiovascular de Colombia | N/A |
| Completed | Efficacy of Bilateral Superficial Cervical Plexus Block vs. Local Infiltration of Lidocaine 2% in Tracheostomy NCT04006639 | Indonesia University | N/A |
| Completed | Pilot Study Evaluating the Success (= Safe Decannulation) of a Standardized Tracheotomy Weaning Procedure in B NCT03512054 | University Hospital, Bordeaux | N/A |
| Completed | Safety of Mechanical Insufflation-exsufflation and Hypertonic Saline NCT03940118 | Hospital San Carlos, Madrid | N/A |
| Completed | Tracheostomy Change NCT04105387 | Children's Hospital of Philadelphia | N/A |
| Completed | Physiological Effects of High-Flow Tracheal Oxygen Via An Modified Interface NCT03244761 | Capital Medical University | — |
| Withdrawn | Randomized Study to Investigate the Safety and Performance of Diaphragm Stimulation Coupled With Mechanical Ve NCT04457427 | Synapse Biomedical | N/A |
| Completed | Reducing Decannulation Time: Limitation of Decannulation Capping Trials (REDECAP) NCT02512744 | Hospital Virgen de la Salud | N/A |
| Unknown | Efficacy of an Early Rehabilitation on Decannulation Time of Patients With Severe Acquired Brain Injury NCT02990871 | Ospedale Generale Di Zona Moriggia-Pelascini | — |
| Completed | Safety of the Nocturnal Passy Muir Valve and Impact on Sleep Quality at an LTACH Setting NCT06229639 | Gaylord Hospital, Inc | N/A |
| Completed | Normal Saline Use With Suctioning NCT02612961 | Johns Hopkins University | N/A |
| Unknown | Comparison Between Immediate and Gradual Decannulation NCT02469909 | Kaplan Medical Center | N/A |
| Completed | Treatment of Tracheostomy Granulomas NCT02116608 | University of Colorado, Denver | Phase 4 |
| Completed | Mechanical Ventilation Discontinuation Practices NCT03955874 | Unity Health Toronto | — |
| Completed | Clinical Assessment of New Speaking Valve With Heat and Moisture Exchanger (HME) for Tracheotomized Patients NCT01976819 | Atos Medical AB | N/A |
| Completed | Scoring Method for Describing the Position of a Tracheostomy Tube NCT01356719 | Manchester University NHS Foundation Trust | — |
| Completed | Does Deflating the Tracheal Cuff Shorten Weaning Time? NCT00956540 | Hospital Virgen de la Salud | Phase 4 |
| Completed | Speech Effects of a Speaking Valve Versus External Positive End-expiratory Pressure (PEEP) in Tracheostomized NCT00978783 | University of Versailles | Phase 2 / Phase 3 |
| Terminated | Azithromycin Treatment of Patients With Chronic Obstructive Pulmonary Disease (COPD) and Tracheostomy NCT00323986 | University of Milan | Phase 2 |